Abstract
Purpose of Review
To describe the main indications and contraindications of transjugular intrahepatic portosystemic shunt (TIPS) placement in patients with portal hypertension (PH).
Recent Findings
An adequate selection of patients helps to identify those who may benefit from TIPS in terms of survival. In patients with acute variceal bleeding and factors of poor prognosis, a pre-emptive use of TIPS is associated with significant reductions in treatment failure and mortality. Similarly, TIPS has shown to improve survival in a highly selected group of patients with cirrhosis and refractory ascites.
Summary
PH is a clinical syndrome associated with the appearance of certain complications which can lead to high morbidity and mortality. TIPS placement effectively reduces portal pressure improving the outcomes of patients who present severe and/or refractory complications of PH. However, an adequate selection of candidates seems to be a key factor for improving the outcomes of patients treated with TIPS.
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This work was sponsored by the Instituto de Salud Carlos III (ISCIII) PI14/00182 and PI17/00298 and the European Union (Fondos FEDER, “Una manera de hacer Europa”). CIBERehd is funded by Instituto de Salud Carlos III.
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Ferrusquía-Acosta, J., Hernández-Gea, V. TIPS Indications and Contraindications—Pushing the Limits: Is Earlier Better?. Curr Hepatology Rep 18, 87–95 (2019). https://doi.org/10.1007/s11901-019-00453-5
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DOI: https://doi.org/10.1007/s11901-019-00453-5