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HCV viral kinetics

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Abstract

Viral kinetics has been and continues to be an important tool for studying hepatitis C virus (HCV) infection and treatment. In this review article the basic principles of viral kinetics as applied to HCV are reviewed. In addition, key insights gained from studies concerning both the mechanism of action of interferon and ribavirin and the life cycle of the virus are discussed. Finally, clinical questions, such as differences in response based on race, genotype, and coinfection that have been examined using kinetics, are discussed.

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Authors and Affiliations

  1. Department of Medicine, University of Illinois Medical Center at Chicago, 1020-N CSB MC 787, 840 South Wood Street, 60612-7323, Chicago, IL, USA

    Jennifer E. Layden-Almer MD

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  1. Jennifer E. Layden-Almer MD
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  2. Scott J. Cotler MD
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  3. Thomas J. Layden MD
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Layden-Almer, J.E., Cotler, S.J. & Layden, T.J. HCV viral kinetics. Curr hepatitis rep 4, 158–161 (2005). https://doi.org/10.1007/s11901-005-0032-2

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  • DOI: https://doi.org/10.1007/s11901-005-0032-2

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