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Exhaled Breath Analysis in Heart Failure

  • Biomarkers of Heart Failure (W H W Tang, Section Editor)
  • Published:
Current Heart Failure Reports Aims and scope Submit manuscript

Abstract

Heart failure (HF) is a clinical condition that presents high morbidity and mortality and is one of the main reasons for hospital admissions all over the world. Although biochemical processes that occur in the body during heart failure are known, this syndrome is still associated to poor prognosis. Exhaled breath analysis has emerged as a promising noninvasive tool in different clinical conditions and, recently, it has been also tested in patients with HF. This review presents the main breath HF biomarkers, which reflect metabolic changes that occur in this complex syndrome. It also discusses the diagnostic and prognostic value of exhaled breath compounds for HF and makes a short description of the main technologies involved in this analysis. Some perspectives on the area are presented as well.

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Authors and Affiliations

  1. Heart Transplant Department, Heart Institute, University of Sao Paulo, São Paulo, Brazil

    Fabiana G. Marcondes-Braga & Fernando Bacal

  2. Chemistry Institute, University of Sao Paulo, São Paulo, Brazil

    Guilherme Lopes Batista & Ivano Gutz

Authors
  1. Fabiana G. Marcondes-Braga
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  2. Guilherme Lopes Batista
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  3. Fernando Bacal
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  4. Ivano Gutz
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Correspondence to Fabiana G. Marcondes-Braga.

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Conflict of Interest

Fabiana G. Marcondes-Braga, Guilherme Lopes Batista, Fernando Bacal, and Ivano Gutz have an issued patent (US, 8,747,325 B2) with the United States Patent and Trademark Office (USPTO) and a pending patent (PCT/BR2011/000227) with Patent Cooperation Treat (PCT).

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Biomarkers of Heart Failure

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Marcondes-Braga, F.G., Batista, G.L., Bacal, F. et al. Exhaled Breath Analysis in Heart Failure. Curr Heart Fail Rep 13, 166–171 (2016). https://doi.org/10.1007/s11897-016-0294-8

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  • DOI: https://doi.org/10.1007/s11897-016-0294-8

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