What Micronutrient Deficiencies Should Be Considered in Distinct Neurological Disorders?


The expanding understanding of the biochemical and physiologic role of micronutrients, commonly referred to as vitamins and minerals, is driving the identification of their consequences in both deficiency and toxicity. Neural tissue is quite sensitive to physiologic changes, and as such, micronutrient deficiencies can have significant and profound effects on the functioning of both the central and peripheral nervous systems. Understanding which micronutrients can affect the nervous system can aid physician identification of these neurological symptoms and signs, leading to diagnostic testing and appropriate therapy.

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Pinckney J. Maxwell IV declares that he has no conflict of interest.

Stephanie C. Montgomery declares that she has no conflict of interest.

Rodrigo Cavallazzi declares that he has no conflict of interest.

Robert G. Martindale declares that he has no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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Correspondence to Pinckney J. Maxwell IV.

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This article is part of the Topical Collection on Nutrition and Obesity

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Maxwell, P.J., Montgomery, S.C., Cavallazzi, R. et al. What Micronutrient Deficiencies Should Be Considered in Distinct Neurological Disorders?. Curr Gastroenterol Rep 15, 331 (2013). https://doi.org/10.1007/s11894-013-0331-7

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  • Micronutrient deficiency
  • Trace mineral deficiency
  • Vitamin deficiency
  • Nutritional deficiency
  • Neurology
  • Neurological disorder
  • Peripheral neuropathy
  • Delirium
  • Encephalopathy
  • Dementia
  • Depression
  • Myelopathy
  • Ataxia
  • Optic neuropathy
  • Night blindness