Current Gastroenterology Reports

, Volume 14, Issue 2, pp 118–124 | Cite as

Chronic Pancreatitis in India and Asia

Pancreas (CE Forsmark, Section Editor)

Abstract

Chronic pancreatitis (CP) is widely prevalent in Asian countries much more so in India and Japan. The phenotype of CP is somewhat similar to that reported from western countries. The prevalent types of CP are mainly idiopathic and alcohol related. Current evidence suggests that the term “tropical pancreatitis” used for idiopathic CP from India is a misnomer. Gallstones’ association with CP reported from China remains controversial. There has been ample evidence that mutations in the SPNIK1 and CFTR genes are strongly associated with idiopathic CP in patients from different ethnic backgrounds. Oxidative stress is important in the pathophysiology and antioxidants have been shown to result in significant pain relief with CP. Home-made balanced diet is effective for treating malnutrition in patients with CP. Endoscopic therapy combined with ESWL may provide significant relief in patients with pancreatic ductal calculi/stricture. Surgery is quite effective in CP and may be better than endotherapy.

Keywords

Chronic pancreatitis Asia India China Japan Genetic mutations SPINK1 CFTR Oxidative stress Antioxidants ERCP ESWL Lateral pancreatojejunostomy 

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of GastroenterologyAll India Institute of Medical SciencesNew DelhiIndia

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