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Preoperative biliary drainage in malignant obstruction: Indications, techniques, and the debate over risk

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Abstract

In patients with malignant biliary obstruction considered suitable for surgical resection, preoperative drainage might be expected to improve surgical outcomes by restoring liver function and improving nutritional status. In practice, however, the benefits of preoperative drainage are far from clear. Studies to date have reported differing outcomes, and some have suggested that morbidity and mortality are greater in patients undergoing drainage than in those proceeding directly to surgery. The development of clinical guidelines has been limited by the lack of convincing randomized data, which in turn has led to variations in practice. This article examines the arguments for and against preoperative biliary drainage, the conflicting data on the subject, and the techniques used.

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References and Recommended Reading

  1. Whipple AO, Parsons WB, Mullins CR: Treatment of carcinoma of the ampulla of Vater. Ann Surg 1935, 102:763–779.

    Article  PubMed  CAS  Google Scholar 

  2. van der Gaag NA, Kloek JJ, de Castro SM, et al.: Preoperative biliary drainage in patients with obstructive jaundice: history and current status. J Gastrointest Surg 2008 Aug 23 (Epub ahead of print).

  3. Blamey SL, Fearon KC, Gilmour WH, et al.: Prediction of risk in biliary surgery. Br J Surg 1983, 70:535–538.

    Article  PubMed  CAS  Google Scholar 

  4. Dixon JM, Armstrong CP, Duffy SW, Davies GC: Factors affecting morbidity and mortality after surgery for obstructive jaundice: a review of 373 patients. Gut 1983, 24:845–852.

    Article  PubMed  CAS  Google Scholar 

  5. McCune WS, Shorb PE, Moscovitz H: Endoscopic cannulation of the ampulla of Vater: a preliminary report. Ann Surg 1968, 167:752–756.

    Article  PubMed  CAS  Google Scholar 

  6. Soehendra N, Reynders-Frederix V: [Palliative biliary duct drainage. A new method for endoscopic introduction of a new drain] [in German]. Dtsch Med Wochenschr 1979, 104:206–207.

    Article  PubMed  CAS  Google Scholar 

  7. Smith AC, Dowsett JF, Russell RC, et al.: Randomised trial of endoscopic stenting versus surgical bypass in malignant low bile duct obstruction. Lancet 1994, 344:1655–1660.

    Article  PubMed  CAS  Google Scholar 

  8. Moss AC, Morris E, Leyden J, Mac Mathuna P: Malignant distal biliary obstruction: a systematic review and metaanalysis of endoscopic and surgical bypass results. Cancer Treat Rev 2007, 33:213–221.

    Article  PubMed  Google Scholar 

  9. Kadakia SC, Starnes E: Comparison of 10 French gauge stent with 11.5 French gauge stent in patients with biliary tract diseases. Gastrointest Endosc 1992, 38:454–459.

    Article  PubMed  CAS  Google Scholar 

  10. Geoghegan JG, Branch MS, Costerton JW, et al.: Placement of biliary stents above the sphincter of Oddi prolongs stent patency in dogs [abstract]. Gut 1991, 32:A1232.

    Google Scholar 

  11. Pedersen FM, Lassen AT, Schaffalitzky de Muckadell OB: Randomized trial of stent placed above and across the sphincter of Oddi in malignant bile duct obstruction. Gastrointest Endosc 1998, 48:574–579.

    Article  PubMed  CAS  Google Scholar 

  12. De Palma GD, Galloro G, Siciliano S, et al.: Unilateral versus bilateral endoscopic hepatic duct drainage in patients with malignant hilar biliary obstruction: results of a prospective, randomized, and controlled study. Gastrointest Endosc 2001, 53:547–553.

    Article  PubMed  Google Scholar 

  13. Tringali A, Mutignani M, Perri V, et al.: A prospective, randomized multicenter trial comparing DoubleLayer and polyethylene stents for malignant distal common bile duct strictures. Endoscopy 2003, 35:992–997.

    Article  PubMed  CAS  Google Scholar 

  14. Moss AC, Morris E, Mac Mathuna P: Palliative biliary stents for obstructing pancreatic carcinoma. Cochrane Database Syst Rev 2006:CD004200.

  15. Wasan SM, Ross WA, Staerkel GA, Lee JH: Use of expandable metallic biliary stents in resectable pancreatic cancer. Am J Gastroenterol 2005, 100:2056–2061.

    Article  PubMed  Google Scholar 

  16. Lawrence C, Howell DA, Conklin DE, et al.: Delayed pancreaticoduodenectomy for cancer patients with prior ERCP-placed, nonforeshortening, self-expanding metal stents: a positive outcome. Gastrointest Endosc 2006, 63:804–807.

    Article  PubMed  Google Scholar 

  17. Kahaleh M, Brock A, Conaway MR, et al.: Covered self-expandable metal stents in pancreatic malignancy regardless of resectability: a new concept validated by a decision analysis. Endoscopy 2007, 39:319–324.

    Article  PubMed  CAS  Google Scholar 

  18. Chen VK, Arguedas MR, Baron TH: Expandable metal biliary stents before pancreaticoduodenectomy for pancreatic cancer: a Monte-Carlo decision analysis. Clin Gastroenterol Hepatol 2005, 3:1229–1237.

    Article  PubMed  Google Scholar 

  19. Speer AG, Cotton PB, Russell RC, et al.: Randomised trial of endoscopic versus percutaneous stent insertion in malignant obstructive jaundice. Lancet 1987, 2(8550):57–62.

    Article  PubMed  CAS  Google Scholar 

  20. Laurent A, Tayar C, Cherqui D: Cholangiocarcinoma: preoperative biliary drainage (Con). HPB (Oxford) 2008, 10:126–129.

    CAS  Google Scholar 

  21. Lai EC, Mok FP, Fan ST, et al.: Preoperative endoscopic drainage for malignant obstructive jaundice. Br J Surg 1994, 81:1195–1198.

    Article  PubMed  CAS  Google Scholar 

  22. Suzuki H, Iyomasa S, Nimura Y, Yoshida S: Internal biliary drainage, unlike external drainage, does not suppress the regeneration of cholestatic rat liver after partial hepatectomy. Hepatology 1994, 20:1318–1322.

    Article  PubMed  CAS  Google Scholar 

  23. Saiki S, Chijiiwa K, Komura M, et al.: Preoperative internal biliary drainage is superior to external biliary drainage in liver regeneration and function after hepatectomy in obstructive jaundiced rats. Ann Surg 1999, 230:655–662.

    Article  PubMed  CAS  Google Scholar 

  24. Heslin MJ, Brooks AD, Hochwald SN, et al.: A preoperative biliary stent is associated with increased complications after pancreatoduodenectomy. Arch Surg 1998, 133:149–154.

    Article  PubMed  CAS  Google Scholar 

  25. Povoski SP, Karpeh MS Jr, Conlon KC, et al.: Association of preoperative biliary drainage with postoperative outcome following pancreaticoduodenectomy. Ann Surg 1999, 230:131–142.

    Article  PubMed  CAS  Google Scholar 

  26. Sohn TA, Yeo CJ, Cameron JL, et al.: Do preoperative biliary stents increase postpancreaticoduodenectomy complications? J Gastrointest Surg 2000, 4:258–267, discussion 267–268.

    Article  PubMed  CAS  Google Scholar 

  27. Limongelli P, Pai M, Bansi D, et al.: Correlation between preoperative biliary drainage, bile duct contamination, and postoperative outcomes for pancreatic surgery. Surgery 2007, 142:313–318.

    Article  PubMed  Google Scholar 

  28. Pisters PW, Hudec WA, Hess KR, et al.: Effect of preoperative biliary decompression on pancreaticoduodenectomy-associated morbidity in 300 consecutive patients. Ann Surg 2001, 234:47–55.

    Article  PubMed  CAS  Google Scholar 

  29. Cortes A, Kianmanesh R, Sauvanet A, et al.: Influence of preoperative endoscopic biliary drainage on postoperative infectious morbidity of duodenopancreatectomy for cancer [abstract 132]. J Gastrointest Surg 2003, 7:299.

    Article  Google Scholar 

  30. Andriulli A, Loperfido S, Napolitano G, et al.: Incidence rates of post-ERCP complications: a systematic survey of prospective studies. Am J Gastroenterol 2007, 102:1781–1788.

    Article  PubMed  Google Scholar 

  31. Sakata J, Shirai Y, Wakai T, et al.: Catheter tract implantation metastases associated with percutaneous biliary drainage for extrahepatic cholangiocarcinoma. World J Gastroenterol 2005, 11:7024–7027.

    PubMed  Google Scholar 

  32. Wagholikar GD, Sikora SS, Pandey R, et al.: Morphological changes in bile ducts following preoperative biliary stenting. Indian J Gastroenterol 2003, 22:166–169.

    PubMed  Google Scholar 

  33. Hodul P, Creech S, Pickleman J, Aranha GV: The effect of preoperative biliary stenting on postoperative complications after pancreaticoduodenectomy. Am J Surg 2003, 186:420–425.

    Article  PubMed  Google Scholar 

  34. Hoffman JP, Lipsitz S, Pisansky T, et al.: Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas: an Eastern Cooperative Oncology Group Study. J Clin Oncol 1998, 16:317–323.

    PubMed  CAS  Google Scholar 

  35. Gerke H, White R, Byrne MF, et al.: Complications of pancreaticoduodenectomy after neoadjuvant chemoradiation in patients with and without preoperative biliary drainage. Dig Liver Dis 2004, 36:412–418.

    PubMed  CAS  Google Scholar 

  36. Pisters PW, Hudec WA, Lee JE, et al.: Preoperative chemoradiation for patients with pancreatic cancer: toxicity of endobiliary stents. J Clin Oncol 2000, 18:860–867.

    PubMed  CAS  Google Scholar 

  37. Belghiti J, Ogata S: Preoperative optimization of the liver for resection in patients with hilar cholangiocarcinoma. HPB (Oxford) 2005, 7:252–253.

    Google Scholar 

  38. Smith RC, Pooley M, George CR, Faithful GR: Preoperative percutaneous transhepatic internal drainage in obstructive jaundice: a randomized, controlled trial examining renal function. Surgery 1985, 97:641–648.

    PubMed  CAS  Google Scholar 

  39. Hatfield AR, Tobias R, Terblanche J, et al.: Preoperative external biliary drainage in obstructive jaundice. Aprospective controlled clinical trial. Lancet 1982, 2(8304):896–899.

    Article  PubMed  CAS  Google Scholar 

  40. McPherson GA, Benjamin IS, Hodgson HJ, et al.: Preoperative percutaneous transhepatic biliary drainage: the results of a controlled trial. Br J Surg 1984, 71:371–375.

    Article  PubMed  CAS  Google Scholar 

  41. Pitt HA, Gomes AS, Lois JF, et al.: Does preoperative percutaneous biliary drainage reduce operative risk or increase hospital cost? Ann Surg 1985, 201:545–553.

    Article  PubMed  CAS  Google Scholar 

  42. Lygidakis NJ, van der Heyde MN, Lubbers MJ: Evaluation of preoperative biliary drainage in the surgical management of pancreatic head carcinoma. Acta Chir Scand 1987, 153:665–668.

    PubMed  CAS  Google Scholar 

  43. Sewnath ME, Karsten TM, Prins MH, et al.: A metaanalysis on the efficacy of preoperative biliary drainage for tumors causing obstructive jaundice. Ann Surg 2002, 236:17–27.

    Article  PubMed  Google Scholar 

  44. Wang Q, Gurusamy KS, Lin H, et al.: Preoperative biliary drainage for obstructive jaundice. Cochrane Database Syst Rev 2008:CD005444.

  45. Mumtaz K, Hamid S, Jafri W: Endoscopic retrograde cholangiopancreaticography with or without stenting in patients with pancreaticobiliary malignancy, prior to surgery. Cochrane Database Syst Rev 2007:CD006001.

  46. Saleh MM, Norregaard P, Jorgensen HL, et al.: Preoperative endoscopic stent placement before pancreaticoduodenectomy: a meta-analysis of the effect on morbidity and mortality. Gastrointest Endosc 2002, 56:529–534.

    Article  PubMed  Google Scholar 

  47. van der Gaag NA, de Castro SM, Rauws EA, et al.: Preoperative biliary drainage for periampullary tumors causing obstructive jaundice; DRainage vs. (direct) OPeration (DROP-trial). BMC Surg 2007, 7:3.

    Article  PubMed  Google Scholar 

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Correspondence to Alan Coss.

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Coss, A., Byrne, M.F. Preoperative biliary drainage in malignant obstruction: Indications, techniques, and the debate over risk. Curr Gastroenterol Rep 11, 145–149 (2009). https://doi.org/10.1007/s11894-009-0022-6

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