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Medical management of postoperative complications of inflammatory bowel disease: Pouchitis and crohn’s disease recurrence

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Abstract

Surgical intervention is often required for patients with inflammatory bowel disease. Total proctocolectomy with ileal pouch-anal anastomosis is the surgical treatment of choice for patients with ulcerative colitis. The main long-term complication of this surgery is pouchitis, with 10-year cumulative incidence rates between 24% and 46%. For patients with Crohn’s disease, postoperative recurrence is a significant problem, with clinical recurrence rates as high as 55% at 5 years and 76% at 15 years. Increasing evidence suggests that postoperative medical therapy has the potential to decrease the risk of postoperative Crohn’s disease recurrence.

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Authors and Affiliations

  1. Department of Gastroenterology, The Cleveland Clinic Foundation, A30, 9500 Euclid Avenue, 44195, Cleveland, OH, USA

    Jean-Paul Achkar MD & Bo Shen MD

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  1. Jean-Paul Achkar MD
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  2. Bo Shen MD
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Achkar, JP., Shen, B. Medical management of postoperative complications of inflammatory bowel disease: Pouchitis and crohn’s disease recurrence. Curr Gastroenterol Rep 3, 484–490 (2001). https://doi.org/10.1007/s11894-001-0069-5

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  • DOI: https://doi.org/10.1007/s11894-001-0069-5

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