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Diabetes in People with HIV

Current Diabetes Reports volume 21, Article number: 13 (2021) Cite this article

Abstract

Purpose of Review

To discuss the diagnosis, treatment, and complications of diabetes in people with HIV (PWH) and to review HIV-related factors that may contribute to the development of diabetes or alter decisions in the care and treatment of PWH with diabetes.

Recent Findings

For those patients with atherosclerotic cardiovascular disease, heart failure, and/or chronic kidney disease, GLP-1 receptor agonists and SGLT-2 inhibitors should be considered for use. Evidence for this recommendation is, however, based on studies that were not conducted in populations consisting solely of PWH.

Summary

Diabetes is a significant comorbidity in PWH and adds to their already heightened risk of cardiovascular disease. HIV-specific factors, including interactions of antiretroviral therapy with medications that either treat diabetes and/or prevent cardiovascular disease, should be evaluated.

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Authors and Affiliations

  1. Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Asthma and Allergy Center 3B.74D, Baltimore, MD, 21224, USA

    Sudipa Sarkar

  2. Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, MD, 21287, USA

    Todd T. Brown

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  1. Sudipa Sarkar
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Correspondence to Sudipa Sarkar.

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This article is part of the Topical Collection on Pharmacologic Treatment of Type 2 Diabetes

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Sarkar, S., Brown, T.T. Diabetes in People with HIV. Curr Diab Rep 21, 13 (2021). https://doi.org/10.1007/s11892-021-01382-8

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Keywords

  • HIV
  • Antiretroviral therapy
  • Diabetes
  • Microvascular complications
  • Macrovascular complications