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Diagnostic Strategies for Gestational Diabetes Mellitus: Review of Current Evidence

  • Diabetes and Pregnancy (M-F Hivert and CE Powe, Section Editors)
  • Published:
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Abstract

Purpose of Review

Currently, the diagnosis of gestational diabetes mellitus (GDM) lacks uniformity. Several controversies are still under debate, especially on the method of screening and diagnosis. This review focuses on recent literature and provides current evidence for the screening and diagnosis of GDM.

Recent Findings

Selective screening would miss a significant number of women with GDM. In contrast, universal screening has been shown to be cost-effective, compared with selective screening, and is recommended by many medical societies. For the diagnostic methods for GDM, most observational cohort studies reported that the one-step method is associated with improved pregnancy outcomes and is cost-saving or cost-effective, compared with the two-step method, although these findings should be confirmed in the upcoming randomized controlled trials which compare the performance of one-step and two-step methods. On the other hand, the methods of early screening or diagnosis of GDM are varied, and current evidence does not justify their use during early pregnancy.

Summary

In conclusion, current evidence favors universal screening for GDM using the one-step method. Early screening for GDM is not favorably supported by the literature.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Kuo, CH., Li, HY. Diagnostic Strategies for Gestational Diabetes Mellitus: Review of Current Evidence. Curr Diab Rep 19, 155 (2019). https://doi.org/10.1007/s11892-019-1271-x

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