Introductory Overview of the Natural Experiments for Translation in Diabetes 2.0 (NEXT-D2) Network: Examining the Impact of US Health Policies and Practices to Prevent Diabetes and Its Complications
Purpose of Review
Diabetes incidence is rising among vulnerable population subgroups including minorities and individuals with limited education. Many diabetes-related programs and public policies are unevaluated while others are analyzed with research designs highly susceptible to bias which can result in flawed conclusions. The Natural Experiments for Translation in Diabetes 2.0 (NEXT-D2) Network includes eight research centers and three funding agencies using rigorous methods to evaluate natural experiments in health policy and program delivery.
NEXT-D2 research studies use quasi-experimental methods to assess three major areas as they relate to diabetes: health insurance expansion; healthcare financing and payment models; and innovations in care coordination. The studies will report on preventive processes, achievement of diabetes care goals, and incidence of complications. Some studies assess healthcare utilization while others focus on patient-reported outcomes.
NEXT-D2 examines the effect of public and private policies on diabetes care and prevention at a critical time, given ongoing and rapid shifts in the US health policy landscape.
KeywordsHealth policy Socio-ecologic framework Quasi-experimental Health outcomes Patient engagement Research dissemination
The authors acknowledge the significant contributions to this study that were provided by collaborating investigators in the NEXT-D2 (Natural Experiments in Translation for Diabetes) Study Two. The authors also acknowledge the participation of our partnering health systems.
This publication was made possible by Cooperative Agreements jointly funded by the US Centers for Disease Control and Prevention (CDC), the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), and the Patient-Centered Outcomes Research Institute (PCORI).
Compliance with Ethical Standards
Conflict of Interest
Drs. O. Kenrik Duru, Carol M. Mangione, Hector P. Rodriguez, Dennis Ross-Degnan, Frank Wharam, Bernard Black, Abel Kho, Nathalie Huguet, Heather Angier, Victoria Mayer, David Siscovick, Jennifer Kraschnewski, Lizheng Shi, Elizabeth Nauman, Edward W. Gregg, Mohammed K. Ali, Pamela Thornton, and Steve Clauser declare that they have no conflict of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. The findings and conclusions in this report are those of the authors and do not necessarily reflect the views of the Patient-Centered Outcomes Research Institute, its Board of Governors, or Methodology Committee.
Papers of particular interest, published recently, have been highlighted as:• Of importance •• Of major importance
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