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Is the Risk and Nature of CVD the Same in Type 1 and Type 2 Diabetes?

  • Macrovascular Complications in Diabetes (PD Reaven, Section Editor)
  • Published:
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Abstract

The incidence of both type 1 and type 2 diabetes is increasing globally, most likely explained by environmental changes, such as changing exposures to foods, viruses, and toxins, and by increasing obesity. While cardiovascular disease (CVD) mortality has been declining recently, this global epidemic of diabetes threatens to stall this trend. CVD is the leading cause of death in both type 1 and type 2 diabetes, with at least a two- to fourfold increased risk in patients with diabetes. In this review, the risk factors for CVD are discussed in the context of type 1 and type 2 diabetes. While traditional risk factors such as dyslipidemia, hypertension, and obesity are greater in type 2 patients than in type 1 diabetes, they explain only about half of the increased CVD risk. The role for diabetes-specific risk factors, including hyperglycemia and kidney complications, is discussed in the context of new study findings.

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Conflict of Interest

Lindsey Duca declares that she has no conflict of interest.

Rachel Sippl declares that she has no conflict of interest.

Janet K. Snell-Bergeon declares that she has no conflict of interest.

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Authors and Affiliations

  1. Colorado School of Public Health, University of Colorado Denver, Anschutz Medical Campus, 13001 E 17th Place, B119, Bldg 500, 3rd Floor, Aurora, CO, 80045, USA

    Lindsey Duca, Rachel Sippl & Janet K. Snell-Bergeon

  2. Barbara Davis Center for Diabetes, University of Colorado Denver, Anschutz Medical Campus, 1775 Aurora Ct, Mail Stop A140, Aurora, CO, 80045, USA

    Rachel Sippl & Janet K. Snell-Bergeon

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  1. Lindsey Duca
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  2. Rachel Sippl
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  3. Janet K. Snell-Bergeon
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Correspondence to Janet K. Snell-Bergeon.

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Duca, L., Sippl, R. & Snell-Bergeon, J.K. Is the Risk and Nature of CVD the Same in Type 1 and Type 2 Diabetes?. Curr Diab Rep 13, 350–361 (2013). https://doi.org/10.1007/s11892-013-0380-1

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