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Metabolic syndrome and major depressive disorder: Co-occurrence and pathophysiologic overlap


The metabolic syndrome and its components are associated with depressive symptomatology. This article discusses the rate of co-occurrence and the points of pathophysiologic commonality between the metabolic syndrome and major depressive disorder.

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Correspondence to Roger S. McIntyre.

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McIntyre, R.S., Rasgon, N.L., Kemp, D.E. et al. Metabolic syndrome and major depressive disorder: Co-occurrence and pathophysiologic overlap. Curr Diab Rep 9, 51–59 (2009).

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  • Depressive Symptom
  • Metabolic Syndrome
  • Bipolar Disorder
  • Mood Disorder
  • Major Depressive Disorder