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The effect of whole organ pancreas transplantation and pit on diabetic complications

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Abstract

Diabetes mellitus is a leading cause of morbidity and mortality in the Western world. Currently, the only forms of β-cell replacement are whole organ pancreas transplantation and pancreatic islet transplantation. Whole organ transplantation has demonstrated benefits in prevention and reversal of diabetic complications with sustainable long-term outcomes. Pancreatic islet transplantation continues to be a field that needs further study to ascertain the true benefit of islet transplantation for diabetic complications. This can only be achieved with improvement in long-term islet allograft survival.

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Authors and Affiliations

  1. Michael E. DeBakey Department of Surgery, Baylor College of Medicine, 1709 Dryden Suite 1500, 77030, Houston, TX, USA

    John A. Goss MD

Authors
  1. Timothy C. Lee dgMD
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  2. Neal R. Barshes MD, MPH
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  3. Erin E. Agee BA
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  4. Christine A. O'Mahoney MD
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  5. F. Charles Brunicardi MD
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  6. John A. Goss MD
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Correspondence to John A. Goss MD.

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Lee, T.C., Barshes, N.R., Agee, E.E. et al. The effect of whole organ pancreas transplantation and pit on diabetic complications. Curr Diab Rep 6, 323–327 (2006). https://doi.org/10.1007/s11892-006-0068-x

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  • DOI: https://doi.org/10.1007/s11892-006-0068-x

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