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Complex Surgical Strategies to Improve Resectability in Borderline-Resectable Disease

Current Colorectal Cancer Reports volume 11, pages 369–377 (2015)Cite this article

Abstract

Colorectal cancer is the third most common malignancy in the USA and continues to pose a significant epidemiologic problem, despite major advances in the treatment of patients with advanced disease. Up to 50 % of patients will develop metastatic disease at some point during the course of their disease, with the liver being the most common site of metastatic disease. In this review, we address the relatively poorly defined entity of borderline-resectable colorectal liver metastases. The workup and staging of borderline-resectable disease are discussed. We then discuss management strategies, including surgical techniques and medical therapies, which are currently utilized in order to improve resectability.

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Motaz Qadan and Michael I. D’Angelica declare that they have no conflict of interest.

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  1. Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, C898, New York, NY, 10065, USA

    Motaz Qadan & Michael I. D’Angelica

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  1. Motaz Qadan
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  2. Michael I. D’Angelica
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Correspondence to Michael I. D’Angelica.

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This article is part of the Topical Collection on Colorectal Cancer Hepatic Metastases

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Qadan, M., D’Angelica, M.I. Complex Surgical Strategies to Improve Resectability in Borderline-Resectable Disease. Curr Colorectal Cancer Rep 11, 369–377 (2015). https://doi.org/10.1007/s11888-015-0290-5

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  • DOI: https://doi.org/10.1007/s11888-015-0290-5

Keywords

  • Colorectal cancer
  • Colorectal liver metastases
  • Liver resection
  • Hepatectomy
  • Two-stage hepatectomy
  • Borderline
  • Borderline-resectable
  • Future liver remnant
  • Portal vein embolization
  • Ablation
  • Systemic chemotherapy
  • Hepatic arterial infusion pump