Current Colorectal Cancer Reports

, Volume 8, Issue 1, pp 16–21

Is There a Place for Screening Flexible Sigmoidoscopy?

Prevention and Early Detection (N Arber, Section Editor)

DOI: 10.1007/s11888-011-0108-z

Cite this article as:
Boltin, D. & Niv, Y. Curr Colorectal Cancer Rep (2012) 8: 16. doi:10.1007/s11888-011-0108-z


Flexible sigmoidoscopy is a valid screening tool for the early detection of colorectal cancer (CRC). Recently published long-term data from UKFSST, a randomized controlled trial, demonstrate a 33% reduction in colorectal cancer incidence and a 43% decrease in colorectal cancer mortality, with once-in-a-lifetime screening. On the other hand, data from the NORCCAP trial with a similar protocol show no reduction in CRC incidence and only nonsignificant decrease in CRC mortality at 7 years. At best, flexible sigmoidoscopy can detect only 70% of cancers and polyps as it does not detect the 40% of proximal neoplasms which are not associated with a distal lesion. The advantage of flexible sigmoidoscopy over other screening modalities lies in its safety profile, patient tolerance, and overall acceptance. Its technical simplicity, short duration, and cost-effectiveness advance its applicability to mass screening programs.


Flexible sigmoidoscopy Screening Colorectal cancer Prevention and early detection 

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Gastroenterology, Rabin Medical CenterTel Aviv UniversityPetach TikvaIsrael

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