Skip to main content

Advertisement

Log in

Methods of Blood Pressure Measurement to Predict Hypertension-Related Cardiovascular Morbidity and Mortality

  • Ischemic Heart Disease (D Mukherjee, Section Editor)
  • Published:
Current Cardiology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

As the evidence on different blood pressure phenotypes and their cardiovascular risks evolve, it is imperative to evaluate the reliability of office blood pressure (OBP), ambulatory blood pressure (ABP), and home blood pressure (HBP) measurements and their associations with cardiovascular morbidity and mortality.

Recent Findings

HBP is more reliable in diagnosis of hypertension than OBP or ABP. HBP correlates better with left ventricular mass index (LVMI). Increasing systolic HBP is associated with a higher risk of all-cause mortality, cardiovascular mortality, and cardiovascular events. An elevated systolic ABP is also associated with a higher risk of cardiovascular events and mortality. ABP is a better predictor of cardiovascular events than OBP in diabetics.

Summary

ABP and HBP furnish additional information beyond OBP. They correlate better with cardiovascular outcomes and are more helpful with monitoring therapy than OBP. Comparative effectiveness studies of all three methods associating with cardiovascular outcomes are warranted.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Viera AJ, Shimbo D, et al. Ambulatory blood pressure phenotypes and the risk for hypertension. Curr Hypertens Rep. 2014;16(10):481. https://doi.org/10.1007/s11906-014-0481-5.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Kaczorowski J, Dawes M, Gelfer M, et al. Measurement of blood pressure: new developments and challenges. BC Med J. 2012;54(8):399–403.

    Google Scholar 

  3. Verdecchia P, Schillaci G, Borgioni C, Ciucci A, Zampi I, Gattobigio R, Sacchi N, Porcellati C, et al. White coat hypertension and white coat effect. Similarities and differences. Am J Hypertens. 1995;8(8):790–8. https://doi.org/10.1016/0895-7061(95)00151-E.

    Article  CAS  PubMed  Google Scholar 

  4. Pickering TG, Gerin W, Schwartz JE, Spruill TM, Davidson KW, et al. Franz Volhard lecture: should doctors still measure blood pressure? The missing patients with masked hypertension. J Hypertens. 2008;26(12):2259–67. https://doi.org/10.1097/HJH.0b013e32831313c4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Banegas JR, Ruilope LM, de la Sierra A, Vinyoles E, Gorostidi M, de la Cruz JJ, Segura J, Oliveras A, Martell N, García-Puig J, Williams B, et al. Clinic versus daytime ambulatory blood pressure difference in hypertensive patients: the impact of age and clinic blood pressure. Hypertension. 2017;69(2):211–9. https://doi.org/10.1161/HYPERTENSIONAHA.116.08567.

    Article  CAS  PubMed  Google Scholar 

  6. Phillips RA, Diamond JA, et al. Ambulatory blood pressure monitoring and echocardiography–noninvasive techniques for evaluation of the hypertensive patient. Prog Cardiovasc Dis. 1999;41(6):397–440. https://doi.org/10.1016/s0033-0620(99)70019-8.

    Article  CAS  PubMed  Google Scholar 

  7. Verberk WJ, Kroon AA, Kessels AG, de Leeuw PW, et al. Home blood pressure measurement: a systematic review. J Am Coll Cardiol. 2005;46(5):743–51. https://doi.org/10.1016/j.jacc.2005.05.058.

    Article  PubMed  Google Scholar 

  8. • Bress AP, Cohen JB, Anstey DE, Conroy MB, Ferdinand KC, Fontil V, Margolis KL, Muntner P, Millar MM, Okuyemi KS, Rakotz MK, Reynolds K, Safford MM, Shimbo D, Stuligross J, Green BB, Mohanty AF, et al. Inequities in hypertension control in the United States exposed and exacerbated by COVID-19 and the role of home blood pressure and virtual health care during and after the COVID-19 pandemic. J Am Heart Assoc. 2021;10(11):e020997. https://doi.org/10.1161/JAHA.121.020997. This study supports the role of community-based interventions and blood pressure self-monitoring to help increase healthcare engagement following COVID-19 mitigation strategies.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Niiranen TJ, Hänninen MR, Johansson J, Reunanen A, Jula AM, et al. Home-measured blood pressure is a stronger predictor of cardiovascular risk than office blood pressure: the Finn-Home study. Hypertension. 2010;55(6):1346–51. https://doi.org/10.1161/HYPERTENSIONAHA.109.149336.

    Article  CAS  PubMed  Google Scholar 

  10. •• Whelton PK, Carey RM, Aronow WS, Casey DE Jr, Collins KJ, Dennison Himmelfarb C, DePalma SM, Gidding S, Jamerson KA, Jones DW, MacLaughlin EJ, Muntner P, Ovbiagele B, Smith SC Jr, Spencer CC, Stafford RS, Taler SJ, Thomas RJ, Williams KA Sr, Williamson JD, Wright JT Jr, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines. J Am Coll Cardiol. 2018;71(19):2199–269. https://doi.org/10.1016/j.jacc.2017.11.005. This report provides current US clinical practice guidelines for prevention, diagnosis, and treatment of hypertension.

    Article  PubMed  Google Scholar 

  11. • Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I, et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension: the Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension. J Hypertens. 2018;36(10):1953–2041. https://doi.org/10.1097/HJH.0000000000001940. This report provides current European clinical practice guidelines for the prevention, diagnosis, and treatment of hypertension.

    Article  CAS  PubMed  Google Scholar 

  12. • Nerenberg KA, Zarnke KB, Leung AA, Dasgupta K, Butalia S, McBrien K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Padwal RS, Tran KC, Grover S, Rabkin SW, Moe GW, Howlett JG, Lindsay P, Hill MD, Sharma M, Field T, Wein TH, Shoamanesh A, Dresser GK, Hamet P, Herman RJ, Burgess E, Gryn SE, Grégoire JC, Lewanczuk R, Poirier L, Campbell TS, Feldman RD, Lavoie KL, Tsuyuki RT, Honos G, Prebtani APH, Kline G, Schiffrin EL, Don-Wauchope A, Tobe SW, Gilbert RE, Leiter LA, Jones C, Woo V, Hegele RA, Selby P, Pipe A, McFarlane PA, Oh P, Gupta M, Bacon SL, Kaczorowski J, Trudeau L, Campbell NRC, Hiremath S, Roerecke M, Arcand J, Ruzicka M, Prasad GVR, Vallée M, Edwards C, Sivapalan P, Penner SB, Fournier A, Benoit G, Feber J, Dionne J, Magee LA, Logan AG, Côté AM, Rey E, Firoz T, Kuyper LM, Gabor JY, Townsend RR, Rabi DM, Daskalopoulou SS, et al. Hypertension Canada’s 2018 guidelines for diagnosis, risk assessment, prevention, and treatment of hypertension in adults and children. Can J Cardiol. 2018;34(5):506–25. https://doi.org/10.1016/j.cjca.2018.02.022. This report provides current Canadian clinical practice guidelines for the prevention, diagnosis, and treatment of hypertension.

    Article  PubMed  Google Scholar 

  13. Shimamoto K, Ando K, Fujita T, Hasebe N, Higaki J, Horiuchi M, Imai Y, Imaizumi T, Ishimitsu T, Ito M, Ito S, Itoh H, Iwao H, Kai H, Kario K, Kashihara N, Kawano Y, Kim-Mitsuyama S, Kimura G, Kohara K, Komuro I, Kumagai H, Matsuura H, Miura K, Morishita R, Naruse M, Node K, Ohya Y, Rakugi H, Saito I, Saitoh S, Shimada K, Shimosawa T, Suzuki H, Tamura K, Tanahashi N, Tsuchihashi T, Uchiyama M, Ueda S, Umemura S, et al. The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2014). Hypertens Res. 2014;37(4):253–390. https://doi.org/10.1038/hr.2014.20.

    Article  PubMed  Google Scholar 

  14. •• Aung K, Htay T, et al. Relationship between outpatient clinic and ambulatory blood pressure measurements and mortality. Curr Cardiol Rep. 2019;21(5):28. https://doi.org/10.1007/s11886-019-1114-z. This review summarizes the relationship between outpatient clinic and ambulatory blood pressure measurements and cardiovascular morbidity and mortality.

    Article  PubMed  Google Scholar 

  15. Bliziotis IA, Destounis A, Stergiou GS, et al. Home versus ambulatory and office blood pressure in predicting target organ damage in hypertension: a systematic review and meta-analysis. J Hypertens. 2012;30(7):1289–99. https://doi.org/10.1097/HJH.0b013e3283531eaf.

    Article  CAS  PubMed  Google Scholar 

  16. Ward AM, Takahashi O, Stevens R, Heneghan C, et al. Home measurement of blood pressure and cardiovascular disease: systematic review and meta-analysis of prospective studies. J Hypertens. 2012;30(3):449–56. https://doi.org/10.1097/HJH.0b013e32834e4aed.

    Article  CAS  PubMed  Google Scholar 

  17. Asayama K, Thijs L, Brguljan-Hitij J, Niiranen TJ, Hozawa A, Boggia J, Aparicio LS, Hara A, Johansson JK, Ohkubo T, Tzourio C, Stergiou GS, Sandoya E, Tsuji I, Jula AM, Imai Y, Staessen JA, et al. Risk stratification by self-measured home blood pressure across categories of conventional blood pressure: a participant-level meta-analysis. PLoS Med. 2014;11(1):e1001591. https://doi.org/10.1371/journal.pmed.1001591.

    Article  PubMed  PubMed Central  Google Scholar 

  18. •• Cardoso CRL, Salles GF, et al. Prognostic impact of home blood pressures for adverse cardiovascular outcomes and mortality in patients with resistant hypertension: a prospective cohort study. Hypertension. 2021;78(5):1617–27. https://doi.org/10.1161/HYPERTENSIONAHA.121.18064. Home blood pressure measurements are predictive of adverse cardiovascular outcomes and improve cardiovascular risk stratification.

    Article  CAS  PubMed  Google Scholar 

  19. Conen D, Bamberg F, et al. Noninvasive 24 h ambulatory blood pressure and cardiovascular disease: a systematic review and meta-analysis. J Hypertens. 2008;26(7):1290–9. https://doi.org/10.1097/HJH.0b013e3282f97854.

    Article  CAS  PubMed  Google Scholar 

  20. Piper MA, Evans CV, Burda BU, Margolis KL, O’Connor E, Whitlock EP, et al. Diagnostic and predictive accuracy of blood pressure screening methods with consideration of rescreening intervals: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2015;162(3):192–204. https://doi.org/10.7326/M14-1539.

    Article  PubMed  Google Scholar 

  21. Shimbo D, Pickering TG, Spruill TM, Abraham D, Schwartz JE, Gerin W, et al. Relative utility of home, ambulatory, and office blood pressures in the prediction of end-organ damage. Am J Hypertens. 2007;20(5):476–82. https://doi.org/10.1016/j.amjhyper.2006.12.011.

    Article  PubMed  Google Scholar 

  22. •• Schwartz JE, Muntner P, Kronish IM, et al. Reliability of office, home, and ambulatory blood pressure measurements and correlation with left ventricular mass. J Am Coll Cardiol. 2020;76(25):2911–22. https://doi.org/10.1016/j.jacc.2020.10.039. Findings from this study demonstrate that HBP is more reliable and strongly associated with LVMI than ABP or OBP.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Tsunoda S, Kawano Y, Horio T, Okuda N, Takishita S, et al. Relationship between home blood pressure and longitudinal changes in target organ damage in treated hypertensive patients. Hypertens Res. 2002;25(2):167–73. https://doi.org/10.1291/hypres.25.167.

    Article  PubMed  Google Scholar 

  24. Mulè G, Caimi G, Cottone S, Nardi E, Andronico G, Piazza G, Volpe V, Federico MR, Cerasola G, et al. Value of home blood pressures as predictor of target organ damage in mild arterial hypertension. J Cardiovasc Risk. 2002;9(2):123–9. https://doi.org/10.1177/174182670200900208.

    Article  PubMed  Google Scholar 

  25. •• Narita K, Hoshide S, Kario K, et al. Difference between morning and evening home blood pressure and cardiovascular events: the J-HOP Study (Japan Morning Surge-Home Blood Pressure). Hypertens Res. 2021. https://doi.org/10.1038/s41440-021-00686-2. This study demonstrates the association between the difference of morning and evening blood pressure and cardiovascular outcomes.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Clement DL, De Buyzere ML, De Bacquer DA, de Leeuw PW, Duprez DA, Fagard RH, Gheeraert PJ, Missault LH, Braun JJ, Six RO, Van Der Niepen P, O’Brien E, et al. Prognostic value of ambulatory blood-pressure recordings in patients with treated hypertension. N Engl J Med. 2003;348(24):2407–15. https://doi.org/10.1056/NEJMoa022273.

    Article  PubMed  Google Scholar 

  27. •• Yang WY, Melgarejo JD, Thijs L, Zhang ZY, Boggia J, Wei FF, Hansen TW, Asayama K, Ohkubo T, Jeppesen J, Dolan E, Stolarz-Skrzypek K, Malyutina S, Casiglia E, Lind L, Filipovský J, Maestre GE, Li Y, Wang JG, Imai Y, Kawecka-Jaszcz K, Sandoya E, Narkiewicz K, O’Brien E, Verhamme P, Staessen JA, et al. International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcomes (IDACO) Investigators. Association of office and ambulatory blood pressure with mortality and cardiovascular outcomes. J Am Med Associ. 2019;322(5):409–20. https://doi.org/10.1001/jama.2019.9811. This study supports that home blood pressure measurements may be considered optimal measurements for assessment of cardiovascular risk.

  28. Parati G, Ochoa JE, Salvi P, Lombardi C, Bilo G, et al. Prognostic value of blood pressure variability and average blood pressure levels in patients with hypertension and diabetes. Diabetes Care. 2013;36(Suppl 2):S312–24. https://doi.org/10.2337/dcS13-2043.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Li Y, Thijs L, Hansen TW, Kikuya M, Boggia J, Richart T, Metoki H, Ohkubo T, Torp-Pedersen C, Kuznetsova T, Stolarz-Skrzypek K, Tikhonoff V, Malyutina S, Casiglia E, Nikitin Y, Sandoya E, Kawecka-Jaszcz K, Ibsen H, Imai Y, Wang J, Staessen JA, et al. Prognostic value of the morning blood pressure surge in 5645 subjects from 8 populations. Hypertension. 2010;55(4):1040–8. https://doi.org/10.1161/HYPERTENSIONAHA.109.137273.

    Article  CAS  PubMed  Google Scholar 

  30. Routledge FS, McFetridge-Durdle JA, Dean CR, et al. Night-time blood pressure patterns and target organ damage: a review. Can J Cardiol. 2007;23(2):132–8. https://doi.org/10.1016/s0828-282x(07)70733-x.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Stevens SL, Wood S, Koshiaris C, Law K, Glasziou P, Stevens RJ, McManus RJ, et al. Blood pressure variability and cardiovascular disease: systematic review and meta-analysis. BMJ. 2016;354:i4098. https://doi.org/10.1136/bmj.i4098.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Ozawa M, Tamura K, Iwatsubo K, Matsushita K, Sakai M, Tsurumi-Ikeya Y, Azuma K, Shigenaga A, Okano Y, Masuda S, Wakui H, Ishigami T, Umemura S, et al. Ambulatory blood pressure variability is increased in diabetic hypertensives. Clin Exp Hypertens. 2008;30(3):213–24. https://doi.org/10.1080/10641960802068477.

    Article  PubMed  Google Scholar 

  33. Stergiou GS, Nasothimiou EG, et al. Home monitoring is the optimal method for assessing blood pressure variability. Hypertens Res. 2011;34(12):1246–8. https://doi.org/10.1038/hr.2011.145.

    Article  PubMed  Google Scholar 

  34. • Gunawan F, Ng HY, Gilfillan C, Anpalahan M, et al. Ambulatory blood pressure monitoring in type 2 diabetes mellitus: a cross-sectional study. Curr Hypertens Rev. 2019;15(2):135–43. https://doi.org/10.2174/1573402114666180607090205. This study demonstrates high prevalence of non-dipping, reverse dipping, nocturnal systolic hypertension, and masked hypertension in type 2 diabetes mellitus.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  35. Gorostidi M, de la Sierra A, González-Albarrán O, Segura J, de la Cruz JJ, Vinyoles E, Llisterri JL, Aranda P, Ruilope LM, Banegas JR, et al. Abnormalities in ambulatory blood pressure monitoring in hypertensive patients with diabetes. Hypertens Res. 2011;34(11):1185–9. https://doi.org/10.1038/hr.2011.100.

    Article  PubMed  Google Scholar 

  36. Uhlig K, Patel K, Ip S, Kitsios GD, Balk EM, et al. Self-measured blood pressure monitoring in the management of hypertension: a systematic review and meta-analysis. Ann Intern Med. 2013;159(3):185–94. https://doi.org/10.7326/0003-4819-159-3-201308060-00008.

    Article  PubMed  Google Scholar 

  37. •• Bryant KB, Sheppard JP, Ruiz-Negrón N, Kronish IM, Fontil V, King JB, Pletcher MJ, Bibbins-Domingo K, Moran AE, McManus RJ, Bellows BK, et al. Impact of self-monitoring of blood pressure on processes of hypertension care and long-term blood pressure control. J Am Heart Assoc. 2020;9(15):e016174. https://doi.org/10.1161/JAHA.120.016174. Self-measured blood pressure monitoring increases the likelihood of intensification of antihypertensive therapy, which can potentially translate to improved blood pressure control.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Fagard RH, Van Den Broeke C, De Cort P, et al. Prognostic significance of blood pressure measured in the office, at home and during ambulatory monitoring in older patients in general practice. J Hum Hypertens. 2005;19(10):801–7. https://doi.org/10.1038/sj.jhh.1001903.

    Article  CAS  PubMed  Google Scholar 

  39. • National Association of Chronic Disease Directors. A national analysis of self-measured blood pressure monitoring coverage and reimbursement. https://chronicdisease.org/page/smbp/. 2020. Accessed 17 Oct 2021. This report summarizes reimbursement of an automatic, upper arm home blood pressure monitor by third-party payors in the USA.

  40. George J, MacDonald T, et al. Home blood pressure monitoring. Eur Cardiol. 2015;10(2):95–101. https://doi.org/10.15420/ecr.2015.10.2.95.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Matsumoto S, Fukui M, Hamaguchi M, et al. Is home blood pressure reporting in patients with type 2 diabetes reliable? Hypertens Res. 2014;37(8):741–5. https://doi.org/10.1038/hr.2014.66.

    Article  CAS  PubMed  Google Scholar 

  42. • National Institute for Health and Care Excellence. Hypertension in adults: diagnosis and management. https://www.nice.org.uk/guidance/ng136. 2019. Accessed 19 Oct 2021. This report provides current UK clinical practice guidelines for the prevention, diagnosis, and treatment of hypertension.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Thwe Htay.

Ethics declarations

Conflict of Interest

The authors declare no competing interests.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical Collection on Ischemic Heart Disease

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Htay, T., Rosado, D., Quest, D. et al. Methods of Blood Pressure Measurement to Predict Hypertension-Related Cardiovascular Morbidity and Mortality. Curr Cardiol Rep 24, 439–444 (2022). https://doi.org/10.1007/s11886-022-01661-0

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11886-022-01661-0

Keywords

Navigation