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Making Sense of High Sensitivity Troponin Assays and their Role in Clinical Care

Current Cardiology Reports volume 16, Article number: 471 (2014) Cite this article

Abstract

Cardiac troponin assays have an established and undisputed role in the diagnosis and risk stratification of patients with acute myocardial infarction. As troponin assays gets more sensitive and more precise, the number of potential uses has rapidly expanded, but the use of this test has also become more complicated and controversial. Highly sensitive troponin assays can now detect troponin levels in most individuals, but accurate interpretation of these levels requires a clear understanding of the assay in the context of the clinical scenario. This paper provides a practical and up-to-date overview of the uses of highly sensitive troponin assays for diagnosis, prognosis, and risk stratification in clinical practice.

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Acknowledgment

This work was supported, in part, by a grant to LBD from the American Heart Association, National Affiliate.

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Conflict of Interest

Lori B. Daniels has received research support from Alere, Critical Diagnostics, and BG Medicine; speaking fees from Critical Diagnostics; and has served on an advisory board for Singulex. She has also been a consultant for Genway and ThermoFisher.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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  1. Division of Cardiology, Department of Medicine, University of California at San Diego, Mail Code 7411,9444 Medical Center Drive, La Jolla, CA, 92037-7411, USA

    Lori B. Daniels

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  1. Lori B. Daniels
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Correspondence to Lori B. Daniels.

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This article is part of the Topical Collection on Interventional Cardiology

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Daniels, L.B. Making Sense of High Sensitivity Troponin Assays and their Role in Clinical Care. Curr Cardiol Rep 16, 471 (2014). https://doi.org/10.1007/s11886-014-0471-x

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Keywords

  • Diagnosis
  • Prognosis
  • Risk stratification
  • Myocardial infarction
  • Prediction
  • High sensitivity troponin assays
  • Clinical care