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Hypertriglyceridemia and risk of coronary heart disease

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Abstract

Mounting evidence indicates that elevated triglyceride level is a risk factor for coronary heart disease (CHD). The role of triglyceride as a causative agent for CHD is less clear. Hyper-triglyceridemia is frequently associated with a set of complex metabolic abnormalities, including low high-density lipoprotein cholesterol, small dense low-density lipoprotein, central obesity, insulin resistance, and type 2 diabetes. Understanding the physiologic processes that lead to the metabolic disturbances associated with hypertriglyceridemia is essential in investigating the effect of triglyceride on CHD risk.

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Hokanson, J.E. Hypertriglyceridemia and risk of coronary heart disease. Curr Cardiol Rep 4, 488–493 (2002). https://doi.org/10.1007/s11886-002-0112-7

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