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Impact of Caffeine on Overactive Bladder Symptoms

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Caffeine consumption is highly prevalent in the adult population. First-line treatment of overactive bladder (OAB) symptoms involves behavioral modification, which includes reduction of caffeine consumption. A literature review over the last 3 years has identified 10 peer-reviewed articles that investigated the effects and mechanisms of caffeine on OAB symptoms. The literature describes that caffeine can be associated to de novo OAB symptoms or their exacerbation. Those effects have been found to be dose dependent. Significant associations to age and gender cannot be made at this point due to limited studies. This review raises awareness of caffeine’s potential causal impact on OAB symptoms, which is important when counseling the general population and patients suffering from OAB. Since there is a lack of evidence-based data to support clinical recommendations, more controlled-randomized prospective studies are needed to assess the impact of caffeine on OAB symptoms that also control for dose, gender, and age.

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United States Food and Drug Administration


Gamma amino butyric acid


Overactive bladder


Quality of life


Urinary incontinence


Urge urinary incontinence


Stress urinary incontinence


Lower urinary tract symptoms


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Correspondence to Andrea Staack.

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Ms. Palma and Dr. Staack declare that they have no conflict of interest.

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This article is part of the Topical Collection on Overactive Bladder

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Palma, IA.F., Staack, A. Impact of Caffeine on Overactive Bladder Symptoms. Curr Bladder Dysfunct Rep 11, 1–7 (2016).

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