Current Bladder Dysfunction Reports

, Volume 8, Issue 1, pp 62–68 | Cite as

Obesity and the Overactive Bladder

Overactive Bladder (A Klausner, Section Editor)

Abstract

Obesity (BMI greater than 30 kg.m-2) and overweight (BMI greater 25-30 kg.m-2) are associated with an increased prevalence of pelvic floor disorders, including urinary incontinence and overactive bladder (OAB) syndrome. A positive association between obesity and OAB is present in women, although it is more difficult to demonstrate in men. OAB may result from several obesity-related conditions including the mechanical effect of increased body mass on the bladder, a result of type-II diabetes or the presence of metabolic syndrome. The underlying metabolic defects of the latter two conditions in generating OAB are discussed. Finally the involvement of endothelial dysfunction as a cause of OAB is considered, as this pathology is a result of several obesity-related conditions.

Keywords

Overactive bladder Obesity Overweight BMI Stress urinary incontinence LUTS Type-II diabetes Metabolic syndrome Hypoxia Reactive oxygen species 

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.The Institute of Biosciences and MedicineUniversity of SurreyGuildfordUK

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