Abstract
Recent studies on asthma have demonstrated multiple phenotypes, based on the clinical characteristics of the disease. With the current interest in personalized medicine, the question arises whether the presence of allergic sensitization has any relevance for these phenotypes and the management of asthma. This review will examine the current knowledge of asthma phenotypes and the impact of atopy on asthma diagnosis and severity in adults. In addition, this review will address whether therapies targeted at the atopic axis help improve asthma outcomes, including lung function indices and exacerbations.
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Sameer K. Mathur has served as a consultant for TEVA, has received grant support from the National Institutes of Health, and served as vice president of the Wisconsin Allergy Society and chair of the AAAAI Asthma and Allergic Diseases in the Elderly Committee.
Ravi K. Viswanathan declares that he has no conflict of interest.
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This article does not contain any studies with human or animal subjects performed by any of the authors.
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Mathur, S.K., Viswanathan, R.K. Relevance of Allergy in Adult Asthma. Curr Allergy Asthma Rep 14, 437 (2014). https://doi.org/10.1007/s11882-014-0437-5
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DOI: https://doi.org/10.1007/s11882-014-0437-5