Current Allergy and Asthma Reports

, Volume 13, Issue 5, pp 518–527

Systemic Contact Dermatitis and Allergy to Biomedical Devices


DOI: 10.1007/s11882-013-0365-9

Cite this article as:
Aquino, M. & Mucci, T. Curr Allergy Asthma Rep (2013) 13: 518. doi:10.1007/s11882-013-0365-9


Systemic contact dermatitis (SCD) refers to a skin condition where an individual who is cutaneously sensitized to an allergen will subsequently react to that same allergen or a cross-reacting allergen via the systemic route. It occurs to allergens including metals, medications, and foods. There has been recent interest in metal allergy as it relates to the implantation of devices such as orthopedic, dental, cardiac, and gynecologic implants. This review will briefly address all causes of systemic contact dermatitis with a special and expanded focus on metal implant allergy. We present literature on SCD to various metal biomedical devices, patch testing for diagnosis of metal allergy pre and post implantation and treatment.


Systemic contact dermatitis Allergic contact dermatitis Metal allergy Orthopedic implant Dental implant Dental amalgam Stent Pacemaker Intrauterine devices Biomedical devices 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Section of Allergy and Clinical ImmunologyWinthrop-University HospitalMineolaUSA
  2. 2.Rheumatology, Allergy & ImmunologyWinthrop University HospitalMineolaUSA

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