Oseltamivir Treatment for Acute Otitis Media in Children with Influenza
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Winther B, Block SL, Reisinger K, Dutkowski R: Impact of oseltamivir treatment on the incidence and course of acute otitis media in children with influenza. Int J Pediatr Otorhinolaryngol 2010, 74:684–688.
••Of major importance.
There are many known risk factors for otitis media, including allergy and infection. In particular, experimental upper respiratory infections with rhinovirus, influenza virus, and respiratory syncytial virus produce nasal obstruction, eustachian tube obstruction, and middle ear under-pressures [1, 2, 3]. However, of these three viruses, only influenza virus infection has been linked to direct visual clinical evidence of otitis media . Furthermore, influenza viruses have been isolated from the middle ear fluid of children with acute otitis media infections. Acute otitis media is the most common complication of pediatric influenza and imposes a substantial health care burden. The medical treatment of otitis media has revolved around...
KeywordsInfluenza Respiratory Syncytial Virus Otitis Medium Acute Otitis Medium Oseltamivir
Dr. Skoner has served on the speakers’ bureau for AstraZeneca, Merck & Co., GlaxoSmithKline, and Novartis; has received grant/research support from Novartis and Schering-Plough; and has served as a consultant for Merck & Co.
- 2.Doyle WJ, Skoner DP, Hayden F, et al.: Nasal and otologic effects of experimental influenza A virus infection. Ann Otol Rhinol Laryngol 1994, l03:59–69.Google Scholar