Skip to main content

Advertisement

Log in

Characteristics of food-allergic patients placing them at risk for a fatal anaphylactic episode

  • Published:
Current Allergy and Asthma Reports Aims and scope Submit manuscript

Abstract

Food allergy is a growing public health and food safety concern. Twelve million Americans—4% of the population—suffer from the disease, and the prevalence is increasing. There is no cure for food allergy; strict avoidance is the only way to prevent a reaction. Food allergy is a major cause of anaphylaxis, a severe, potentially life-threatening allergic reaction that results in an estimated 30,000 emergency department visits and 100 to 150 deaths annually. Factors that place food-allergic patients at greater risk for a fatal anaphylactic episode include asthma; being a teen or young adult; peanut, tree nut, and seafood allergy; not carrying epinephrine; restaurant food; spending time in schools and child care settings; and lack of information from health care providers. Better education of patients and their families about managing their food allergy and high-risk situations can help to prevent future fatalities.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References and Recommended Reading

  1. National Institutes of Health, National Institute of Allergy and Infectious Disease: Report of the NIH Expert Panel on food allergy research, March 13–14, 2006. Available at http://www3.niaid.nih.gov/topics/foodAllergy/research/ReportFoodAllergy.htm. Accessed June 2008.

  2. Sicherer SH, Muñoz-Furlong A, Sampson HA: Prevalence of peanut and tree nut allergy in the United States determined by means of a random digit dial telephone survey: a 5-year follow-up study. J Allergy Clin Immunol 2003, 112:1203–1207.

    Article  PubMed  Google Scholar 

  3. Grundy J, Matthews S, Bateman B, et al.: Rising prevalence of allergy to peanut in children: data from 2 sequential cohorts. J Allergy Clin Immunol 2002, 110:784–789.

    Article  PubMed  Google Scholar 

  4. Weiss C, Muñoz-Furlong A, Furlong TJ, Arbit J: Impact of food allergies on school nursing practice. J Sch Nurs 2004, 20:268–278.

    Article  PubMed  Google Scholar 

  5. Sicherer SH, Sampson HA: Peanut allergy: emerging concepts and approaches for an apparent epidemic. J Allergy Clin Immunol 2007, 120:491–503.

    Article  PubMed  Google Scholar 

  6. Beyer K, Morrow E, Li XM, et al.: Effects of cooking methods on peanut allergenicity. J Allergy Clin Immunol 2001, 107:1077–1081.

    Article  PubMed  CAS  Google Scholar 

  7. Sicherer SH, Furlong TJ, Maes HH, et al.: Genetics of peanut allergy: a twin study. J Allergy Clin Immunol 2000, 106:53–56.

    Article  PubMed  CAS  Google Scholar 

  8. US Food and Drug Administration, Center for Food Safety and Applied Nutrition: Questions and answers regarding food allergens, including the Food Allergen Labeling and Consumer Protection Act of 2004 (Edition 4). Available at http://www.cfsan.fda.gov/:_dms/alrguid4.html. Accessed June 2008.

  9. Centers for Disease Control, National Center for Chronic Disease Prevention and Health Promotion: Healthy youth! Available at http://www.cdc.gov/HealthyYouth/foodallergies/. Accessed June 2008.

  10. Sicherer SH, Muñoz-Furlong A, Sampson HA: Prevalence of seafood allergy in the United States determined by a random telephone survey. J Allergy Clin Immunol 2004, 114:159–165.

    Article  PubMed  Google Scholar 

  11. Baral VR, Hourihane JO: Food allergy in children. Post-grad Med J 2005, 81:693–701.

    Article  CAS  Google Scholar 

  12. Skripak JM, Wood RA: Peanut and tree nut allergy in childhood. Pediatr Allergy Immunol 2008, 19:368–373.

    Article  PubMed  Google Scholar 

  13. Skripak JM, Matsui EC, Mudd K, Wood RA: The natural history of IgE-mediated cow’s milk allergy. J Allergy Clin Immunol 2007, 120:1172–1177.

    Article  PubMed  CAS  Google Scholar 

  14. Sampson HA: Food allergy. J Allergy Clin Immunol 2003, 111:8540–8547.

    Article  CAS  Google Scholar 

  15. US Food and Drug Administration: Food allergies: what you need to know. Available at http://www.cfsan.fda.gov/:_dms/ffalrgn.html. Accessed June 2008.

  16. Sampson HA, Muñoz-Furlong A, Campbell RL, et al.: Second symposium on the definition and management of anaphylaxis: summary report-Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol 2006, 117:391–397.

    Article  PubMed  Google Scholar 

  17. Sicherer SH, Furlong TJ, DeSimone J, Sampson HA: The U.S. peanut and tree nut allergy registry: characteristics of reactions in schools and child care. J Pediatr 2001, 138:560–565.

    Article  PubMed  CAS  Google Scholar 

  18. Sicherer SH, Furlong TJ, DeSimone J, Sampson HA: Self-reported allergic reactions to peanut on commercial airliners. J Allergy Clin Immunol 1999, 104:25–27.

    Article  Google Scholar 

  19. Comstock SS, DeMera R, Vega LC, et al.: Allergic reactions to peanuts, tree nuts, and seeds aboard commercial airliners. Ann Allergy Asthma Immunol 2008, 101:51–56.

    PubMed  Google Scholar 

  20. The Food Allergy & Anaphylaxis Network: Frequently asked questions about anaphylaxis. Available at http://www.foodallergy.org/anaphylaxis/index.html. Accessed June 2008.

  21. Yocum MW, Butterfield JH, Klein JS, et al.: Epidemiology of anaphylaxis in Olmstead County: a population-based study. J Allergy Clin Immunol 1999, 104:271–273.

    Article  Google Scholar 

  22. Ross MP, Ferguson M, Street D, et al.: Analysis of food-allergic and anaphylactic events in the National Electronic Injury Surveillance System. J Allergy Clin Immunol 2008, 121:166–171.

    Article  PubMed  Google Scholar 

  23. Vander Leek TK, Liu AH, Stefanski K, et al.: The natural history of peanut allergy in young children and its association with serum peanut-specific IgE. J Pediatr 2000, 137:749–755.

    Article  Google Scholar 

  24. Hefle SL, Furlong TJ, Niemann L, et al.: Consumer attitudes and risks associated with packaged goods having advisory labeling regarding the presence of peanuts. J Allergy Clin Immunol 2007, 120:171–176.

    Article  PubMed  Google Scholar 

  25. Bock SA, Muñoz-Furlong A, Sampson HA: Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol 2001, 107:191–193.

    Article  PubMed  CAS  Google Scholar 

  26. Bock SA, Muñoz-Furlong A, Sampson HA: Further fatalities due to anaphylactic reactions to food: 2001 to 2006. J Allergy Clin Immunol 2007, 119:1016–1018.

    Article  PubMed  Google Scholar 

  27. Pumphrey RSH, Gowland MH: Further fatal allergic reactions to food in the United Kingdom, 1999–2006. J Allergy Clin Immunol 2007, 119:1018–1019.

    Article  PubMed  Google Scholar 

  28. Yunginger JW, Sweeney KG, Sturner WQ, et al.: Fatal food-induced anaphylaxis. JAMA 1988, 260:1450–1452.

    Article  PubMed  CAS  Google Scholar 

  29. Sampson HA, Mendelson L, Rosen JP: Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med 1992, 327:380–384.

    PubMed  CAS  Google Scholar 

  30. Sampson HA, Muñoz-Furlong A, Sicherer SH: Risk-taking and coping strategies of food-allergic adolescents and young adults. J Allergy Clin Immunol 2006, 117:1440–1445.

    Article  PubMed  Google Scholar 

  31. Korenblat P, Lundie MJ, Dankner RE, Day JH: A retrospective study of epinephrine administration for anaphylaxis: how many doses are needed? Allergy Asthma Proc 1999, 20:383–386.

    Article  PubMed  CAS  Google Scholar 

  32. Oren E, Banerji A, Clark S, Camargo CA: Food-induced anaphylaxis and repeated epinephrine treatments. Ann Allergy 2007, 99:429–432.

    Article  CAS  Google Scholar 

  33. Furlong TJ, DeSimone J, Sicherer SH: Peanut and tree nut allergic reactions in restaurants and other food establishments. J Allergy Clin Immunol 2001, 108:867–870.

    Article  PubMed  CAS  Google Scholar 

  34. Eigenmann PA, Zamora SA: An Internet-based survey on the circumstances of food-induced reactions following the diagnosis of IgE-mediated food allergy. Allergy 2002, 57:449–453.

    Article  PubMed  CAS  Google Scholar 

  35. Nowak-Wegrzyn A, Conover-Walker MK, Wood RA: Food-allergic reactions in schools and preschools. Arch Pediatr Adolesc Med 2001, 155:790–795.

    PubMed  CAS  Google Scholar 

  36. Clark S, Bock SA, Gaeta TJ, et al.: Multicenter study of emergency department visits for food allergies. J Allergy Clin Immunol 2004, 113:347–352.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Christopher C. Weiss.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Muñoz-Furlong, A., Weiss, C.C. Characteristics of food-allergic patients placing them at risk for a fatal anaphylactic episode. Curr Allergy Asthma Rep 9, 57–63 (2009). https://doi.org/10.1007/s11882-009-0009-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11882-009-0009-2

Keywords

Navigation