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Are barrier creams actually effective?

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Abstract

This article reviews the current information surrounding the efficacy of barrier creams as a protective measure against contact dermatitis. The principles of the proposed effects of barrier creams on the skin and the experimental and clinical data regarding their efficacy in the prevention of irritant and allergic contact dermatitis are discussed.

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References and Recommended Reading

  1. Cohen DE, Brancaccio RR, Soter NA: Diagnostic tests for type IV or delayed hypersensitivity reaction. In Diagnostic Testing of Allergic Disease. Edited by Kemp SF, Lockley RF. New York: Marcel Dekker; 2000:289–305.

    Google Scholar 

  2. Sedenari S: Evaluation of barrier function and skin reactivity in occupational dermatoses. In Handbook of Occupational Dermatology. Edited by Kanerva L, Elsner P, Wahlberg JE, Maibach HI. New York: Springer-Verlag; 2000:64–75.

    Google Scholar 

  3. Davidson CL: Occupational contact dermatitis of the upper extremity. In Occupational Medicine: State of the Art Reviews. Philadelphia: Hanley and Belfus; 1994:59–73.

    Google Scholar 

  4. Frosch PJ, Schulze-Dirks A, Hoffman M, et al.: Efficacy of skin barrier creams (II): ineffectiveness of a popular "skin protector" against various irritants in the repetitive irritation test in the guinea pig. Contact Dermatitis 1993, 29:74–77.

    Article  PubMed  CAS  Google Scholar 

  5. Wigger-Alberti W, Elsner P: Barrier creams and emollients. In Handbook of Occupational Dermatology. Edited by Kanerva L, Elsner P, Wahlberg JE, Maibach HI. New York: Springer-Verlag; 2000:490–496. This is a comprehensive textbook review of BCs and a good reference source.

    Google Scholar 

  6. Wigger-Alberti W, Caduff L, Burg G, Elsner P: Experimentally induced chronic irritant contact dermatitis to evaluate the efficacy of protective creams in vivo. J Am Acad Dermatol 1999, 40:590–596.

    Article  PubMed  CAS  Google Scholar 

  7. Goh CL: Cutting oil dermatitis on guinea pig skin (I): cutting oil dermatitis and barrier cream. Contact Dermatitis 1991, 24:16–21.

    Article  PubMed  CAS  Google Scholar 

  8. Frosch PJ, Kurte A: Efficacy of skin barrier creams (IV): the repetitive irritation test (RIT) with a set of 4 standard irritants. Contact Dermatitis 1994, 31:161–168.

    Article  PubMed  CAS  Google Scholar 

  9. Frosch PJ, Shulze-Dorks A, Hoffman M, et al.: Efficacy of skin barrier creams (I): the repetitive test (RIT) in the guinea pig. Contact Dermatitis 1993, 28:94–100.

    Article  PubMed  CAS  Google Scholar 

  10. Frosch PJ, Kurte A, Pilz B: Efficacy of skin barrier creams (III): the repetitive irritation test (RIT) in humans. Contact Dermatitis 1993, 29:113–118.

    Article  PubMed  CAS  Google Scholar 

  11. Schluter-Wigger W, Elsner P: Efficacy of 4 commercially available protective creams in the repetitive irritation test (RIT). Contact Dermatitis 1996, 34:278–283.

    Article  PubMed  CAS  Google Scholar 

  12. Elsner P, Wigger-Alberti A, Pantini G: Perfluoropolyethers in the prevention of irritant contact dermatitis. Dermatology 1998, 197:141–145.

    Article  PubMed  CAS  Google Scholar 

  13. Wigger-Alberti W, Elsner P: Petrolatum prevents irritation in a human cumulative exposure model in vivo. Dermatology 1997, 194:247–250.

    PubMed  CAS  Google Scholar 

  14. Zhai H, Maibach HI: Effect of barrier creams: human skin in vivo. Contact Dermatitis 1996, 35:92–96.

    Article  PubMed  CAS  Google Scholar 

  15. Patterson SE, Williams JV, Marks JG Jr: Prevention of sodium lauryl sulfate irritant contact dermatitis by Pro-Q aerosol foam skin protectant. J Am Acad Dermatol 1999, 40:783–785.

    Article  PubMed  CAS  Google Scholar 

  16. Fowler JF: Efficacy of a skin-protective foam in the treatment of chronic hand dermatitis. Am J Contact Dermat 2000, 33:165–169. This is one of the few clinical studies evaluating BCs in chronic hand dermatitis.

    Article  Google Scholar 

  17. Berndt U, Wigger-Alberti W, Gabard B, Elsner P: Efficacy of a barrier cream and its vehicle as protective measures against occupational irritant contact dermatitis. Contact Dermatitis 2000, 42:77–80. This is a negative study demonstrating that the vehicle was as effective as the BC used.

    Article  PubMed  CAS  Google Scholar 

  18. Long D, Ballentine NH, Marks JG Jr: Treatment of poison ivy/ oak allergic contact dermatitis with an extract of jewelweed. Am J Contact Dermat 1997, 8:150–153.

    Article  PubMed  CAS  Google Scholar 

  19. Gibson MR, Maher FT: Activity for jewelweed and its enzymes in the treatment of Rhus dermatitis. J Am Pharm Assoc 1950, 39:294–296.

    CAS  Google Scholar 

  20. Lipton RA: The use of Impatiens biflora (jewelweed) in the treatment of Rhus dermatitis. Ann Allergy 1958, 16:526–527.

    PubMed  CAS  Google Scholar 

  21. Guin JD, Reynolds R: Jewelweed treatment of poison ivy dermatitis. Contact Dermatitis 1980, 6:287–288.

    Article  PubMed  CAS  Google Scholar 

  22. Orchard SO, Fellman JH, Storrs FJ: Poison ivy/oak dermatitis. Arch Dermatol 1986, 122:283–289.

    Article  Google Scholar 

  23. Marks JG, Fowler JF Jr, Sheretz EF, Rietschel RL: Prevention of poison ivy and poison oak allergic contact dermatitis by quaterium-18 bentonite. J Am Acad Dermatol 1995, 33:212–216.

    Article  PubMed  Google Scholar 

  24. Vidmar DA, Iwane MK: Assessment of the ability of the topical skin protectant (TSP) to protect against contact dermatitis to urushiol (rhus) antigen. Am J Contact Dermat 1999, 10:190–197.

    Article  PubMed  CAS  Google Scholar 

  25. Gawkrodger DJ, Healy J, Howe AM: The prevention of nickel contact dermatitis: a review of the use of binding agents and barrier creams. Contact Dermatitis 1995, 32:257–265.

    Article  PubMed  CAS  Google Scholar 

  26. Wigger-Alberti W, Maraffio B, Wernli M, et al.: Self-application of a protective cream: pitfalls of occupational skin protection. Arch Dermatol 1997, 133:861–864.

    Article  PubMed  CAS  Google Scholar 

  27. Wigger-Alberti W, Maraffio B, Wernli M, et al.: Training workers at risk for occupational contact dermatitis in the application of protective creams: efficacy of a fluorescence technique. Dermatology 1997, 195:129–133.

    Article  PubMed  CAS  Google Scholar 

  28. Wigger-Alberti W, Elsner P: Do barrier creams and gloves prevent or provoke contact dermatitis? Am J Contact Dermat 1998, 9:100–106. This is an excellent review of the problems regarding the efficacy of BCs.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Ronald O. Perelman Department of Dermatology, New York University, School of Medicine, The Skin Institute of New York, 67 Perry Street, 10014, New York, Y, USA

    Marcy S. Alvarez BS, Lance H. Brown MD & Ronald R. Brancaccio MD

Authors
  1. Marcy S. Alvarez BS
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  2. Lance H. Brown MD
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  3. Ronald R. Brancaccio MD
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Alvarez, M.S., Brown, L.H. & Brancaccio, R.R. Are barrier creams actually effective?. Curr Allergy Asthma Rep 1, 337–341 (2001). https://doi.org/10.1007/s11882-001-0045-z

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  • DOI: https://doi.org/10.1007/s11882-001-0045-z

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