Effect of pollutants in rhinitis

  • David B. Peden
Article

Abstract

Allergic rhinitis is a very common disease worldwide and is influenced by both genetic and environmental factors. Exposure to environmental allergens is the most significant environmental factor in development and exacerbation of allergic rhinitis. However, air pollutants that are not allergens may affect allergic inflammation in the nasal airway. The nasal airway possesses a number of defense mechanisms to deal with environmental irritants. This article examines the effect of ozone and particulate air pollution on TH2-type inflammation in the airway and how nasal defenses protect the upper and lower airway from adverse effects of pollutants.

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Copyright information

© Current Science Inc 2001

Authors and Affiliations

  • David B. Peden
    • 1
  1. 1.Center for Environmental Medicine & Lung BiologyUniversity of North Carolina at Chapel HillChapel HillUSA

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