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Role of Stereotactic Radiation Therapy in Operable and Inoperable Early-Stage Non-small Cell Lung Cancer

  • Lung Cancer (TA Leal and N Sethakorn, Section Editors)
  • Published:
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Radiation therapy is becoming an increasingly important part of non-small cell lung cancer (NSCLC) management. Approximately 60% of all cancer patients require radiation therapy (RT) as part of their treatment. For lung cancer, this number is even higher, reaching approximately 77% of all patients, from radical to palliative modalities of RT. This percentage may even be underestimated, as it may not account for the more recent use of RT in oligometastatic lung cancer patients. Thus, we can estimate that each year there will be approximately 21,890 new lung cancer patients in the USA requiring RT. These numbers are expected to continue to rise, as lung cancer radiation techniques continue to improve. There is growing interest in determining the best treatment options for early-stage NSCLC patients. There is well-established data showing the benefit of RT for inoperable patients, and more recent encouraging data even in operable patients.

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Correspondence to Lilian Faroni MD, PhD.

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Lilian Faroni declares that she has no conflict of interest. Laura Collie declares that he has no conflict of interest. Flavia Gabrielli declares that she has no conflict of interest. Clarissa Baldotto has served as a consultant/advisory board member for Astra Zeneca, Novartis, MSD, and Roche. Fabio Ynoe de Moraes (FYM) received honoraria from Astra Zeneca and IASLC outside the submitted work. FYM declares grants or contracts from CTAQ Queen’s University outside the current work. FYM has received consulting fees from Cancer em foco outside of the submitted work.

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Faroni, L., Collie, L., Gabrielli, F. et al. Role of Stereotactic Radiation Therapy in Operable and Inoperable Early-Stage Non-small Cell Lung Cancer. Curr. Treat. Options in Oncol. 23, 1185–1200 (2022). https://doi.org/10.1007/s11864-022-01002-x

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