Skip to main content
Log in

New abnormal cervical cell detection method of multi-spectral pap smears

  • Published:
Wuhan University Journal of Natural Sciences

Abstract

Considering the problem of traditional cervical cancer detection method that brings high false negative rate (FNR) and high false positive rate (FPR), a new abnormal cervical cells detection method of multi-spectral Pap smear is proposed in this thesis, on the basis of multi-spectral microscopic imaging technology and computer automotive recognition technology. At first, image in a specific wave band is segmented according to the relationship between intensity and spectrum of each pixel. Then, multi-spectral features of each pixel are extracted making use of improved cosine correlation analysis (CCA) algorithm. Combined with the characteristic of each cell’s area, final definition is made. Experiments have proved the new approach could identify abnormal cells efficiently as well as lower FNR and FPR.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Zhao Fanghui, Rong Shoude, Qiao Youlin. Cervical Cancer and the Examination of Pathological Changes[J]. Medical Science Transaction of China, 2001, 23(6): 638–641 (Ch).

    Google Scholar 

  2. Koss L G. The Papanicolaou Test for Cervical Cancer Detection—a Triumph and Tragedy[J]. J Am Med Assoc, 1989, 261:737–741.

    Article  Google Scholar 

  3. Liu Yanxi, Zhao Tong, Zhang Jiayong. Learning Multispectral Texture Features for Cervical Cancer Detection[J]. 2002 IEEE International Symposium on, 2002, 7(10):169–172.

    MATH  Google Scholar 

  4. Galbraith W, Marshall P N, Lee E S, et al. Studies on Papanicolaou Staining I: Visible-Light Spectra of Stained Cervical Cells[J]. Analytical and Quantitative Cytology and Histology, 1979, 1(3): 160–169.

    Google Scholar 

  5. Walts A E, Thomas P. Endometrial Cells and the AutoPap System for Primary Screening of Cervicovaginal Pap Smears. Diagn Cytopathol, 2002, 27(4):232–237.

    Article  Google Scholar 

  6. Wilbur D C, Parker E M, Foti J A. Use of Automated Primary Screening on Liquid-Based, Thin-Layer Preparations[J]. ActaCytol, 2002, 46(2):291–295.

    Google Scholar 

  7. Wilbur D C, Norton M K. The Primary Screening Clinical Trials of the TriPath AutoPap System. Epidemiology, 2002, 13(3 Suppl):S30–S33.

    Article  Google Scholar 

  8. Zhang Huiying, Tan Yubin. Cell Pathological Identification and Diagnoses of Color Spectrum—Shelling and Puncture Cell Pathology[M]. Tianjing; Tianjing Scientific Translation Press, 2004(Ch).

    Google Scholar 

  9. Turner J F, Zhang J, O’Connor A, A Spectral Identity Mapper for Chemical Image Analysis[J]. Applied Spectroscopy, 2004, 58(11): 1308–1317.

    Article  Google Scholar 

  10. Zhang J, O’Connor A, Turner J F. Cosine Histogram Analysis for Spectral Image Data Classification[J]. Applied Spectroscopy, 2004, 58(11): 1318–1324.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Chen Shuzhen.

Additional information

Foundation item: Supported by Key Project of the Tenth Five-Year Plan of the Ministry of Science and Technology of China (2001BA210A02)

Biography: CAO Feng(1979–), male, Ph.D. candidate, research direction: multimedia signal processing, network communication.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cao, F., Chen, S. & Zeng, L. New abnormal cervical cell detection method of multi-spectral pap smears. Wuhan Univ. J. of Nat. Sci. 12, 476–480 (2007). https://doi.org/10.1007/s11859-006-0108-z

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11859-006-0108-z

Key words

CLC number

Navigation