Abstract
Background
Recurrent miscarriage affects 1–2% of the population, and the literature has focussed on causes, treatment, and live birth rate.
Aim
This study aimed to assess the reproductive outcomes for patients who attended a specialist recurrent miscarriage clinic for investigation and treatment.
Methods
Prospective analysis of all patients who attended a recurrent miscarriage clinic from January 2014 to January 2021.
Results
Of the 488 patients who attended a specialist clinic, 318 had a further pregnancy with 299 included in this study. The median age was 37 years, with 55.6% having a previous live birth. The subsequent live birth rate was 75.3%, 22.0% had a further pregnancy loss, 1.7% had an ongoing pregnancy, and 1% attended another institution after the second trimester. The rate of preeclampsia was 2.2%, pregnancy-induced hypertension was 2.2%, fetal growth restriction was 5.3%, preterm birth ≤ 34 weeks was 1.8%, and preterm birth > 34 weeks < 37 weeks was 6.6%.
Conclusion
Patients who attend a dedicated recurrent miscarriage clinic for investigation and treatment have a high live birth rate in a subsequent pregnancy. A subsequent pregnancy following recurrent pregnancy loss does not appear to be associated with an increased risk of adverse pregnancy outcomes.
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DC, SD, and CA planned the study; NF, AMcE, and SC undertook data collection; NF interpreted the results and drafted the manuscript; and DC, CA, and SC revised the manuscript. All gave final approval.
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This study attained full ethical approval from the National Maternity Hospital Ethics Committee.
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The authors declare no competing interests.
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Fee, N., McEvoy, A., Cullen, S. et al. Pregnancy outcomes following recurrent miscarriage. Ir J Med Sci 192, 2255–2258 (2023). https://doi.org/10.1007/s11845-023-03305-w
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DOI: https://doi.org/10.1007/s11845-023-03305-w