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Festschrift for Ronan O’Connell: pouchitis, ulcerative colitis and the microbiome

Irish Journal of Medical Science (1971 -) volume 187, pages 1133–1137 (2018)Cite this article

Abstract

The hypothesis of altered bacterial communities contributing to the development of pouchitis began a scientific quest to link host mucosal factors, microbial metabolism and spatial structure of the colonic microbiome in ulcerative colitis, reaching its apotheosis with the integration of advanced spatial sampling with laser capture microdissection, mucin array profiling, molecular microbiology and next-generation sequencing technologies. This article, part of a festschrift, summarises the contributions of the O’Connell lab to the field of host-microbial interactions in inflammatory bowel disease.

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Authors and Affiliations

  1. Department of Medicine, APC Microbiome Ireland, University College Cork, Cork, Ireland

    Aonghus Lavelle

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  1. Aonghus Lavelle
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Correspondence to Aonghus Lavelle.

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Lavelle, A. Festschrift for Ronan O’Connell: pouchitis, ulcerative colitis and the microbiome. Ir J Med Sci 187, 1133–1137 (2018). https://doi.org/10.1007/s11845-018-1785-2

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  • DOI: https://doi.org/10.1007/s11845-018-1785-2

Keywords

  • Inflammatory bowel disease
  • Microbiome
  • Pouchitis