Clinical outcomes following spinal fracture in patients with ankylosing spondylitis
- 264 Downloads
Ankylosing spondylitis is a seronegative rheumatoid condition mainly affecting the axial skeleton. It leads to progressive deformity and stiffening of the spine with an increased risk of vertebral fractures and significant neurological deficits compared to the general population.
This study aimed to evaluate the outcomes of patients with ankylosing spondylitis who sustained acute vertebral fractures over a 10-year period.
A retrospective review of patient records and radiographic images was performed. Mechanism of injury, fracture type, timing of diagnosis, neurological deficit, management and complications were assessed.
Twenty-four patients were included. Most (23) sustained low energy injuries. Five (20%) patients had a delayed diagnosis over 24 h after the time of injury. Twelve (50%) of patients had a neurological deficit at the time of admission and most did not recover. Eighteen (75%) patients underwent surgical stabilisation. There were 19 complications (in 15 patients) following surgery.
Patients with ankylosing spondylitis are at risk of spinal fracture and associated spinal cord injury after relatively minor trauma. Delayed diagnosis places the patient at risk of neurological compromise, and thus a high index of suspicion is needed when assessing this patient group.
KeywordsAnkylosing spondylitis Spinal fracture Trauma Outcomes Spinal cord injury
Compliance with ethical standards
The authors received no funding for this work and declare no conflict of interest. As this was a retrospective study and involved no intervention or change in treatment, consent was not necessary.
- 13.International Standards for the Neurological Classification of Spinal Cord Injury, Revised 2015 [booklet]. Atlanta, GA: American Spinal Injury AssociationGoogle Scholar
- 23.Lukasiewicz AM1, Bohl DD, Varthi AG, Basques BA, Webb ML, Samuel AM, Grauer JN (2016) Spinal Fracture in Patients With Ankylosing Spondylitis: Cohort Definition, Distribution of Injuries, and Hospital Outcomes. Spine (Phila Pa 1976) 41(3):191–6Google Scholar