References
Latif Z, Malik MA, Jabbar F, Ahmed Y, McDonough C (2010) Clozapine-induced late leukopenia. Ir J Med Sci. doi: 10.1007/s11845-010-0587-y
Bhanji NH, Margolese HC, Chouinard G, Turnier L (2003) Late-onset agranulocytosis in a patient with schizophrenia after 17 months of clozapine treatment. J Clin Psychopharmacol 23(5):522–523
Sedky K, Shaughnessy R, Hughes T, Lippmann S (2005) Clozapine-induced agranulocytosis after 11 years of treatment. Am J Psychiatry 162(4):814
Tamam L, Kulan E, Ozpoyraz N (2001) Late onset neutropenia during clozapine treatment. Psychiatry Clin Neurosci 55(5):547–548
Tiihonen J (2006) Fatal agranulocytosis 4 years after discontinuation of clozapine. Am J Psychiatry 163(1):161
Emea (2011) http://www.emea.europa.eu/pdfs/human/referral/603402en.pdf. Accessed 2 Feb 2011
FDA (2011) http://www.fda.gov/cder/foi/label/2005/019758s056lbl.pdf. Accessed 2 Feb 2011
Heimpel H (1991) The diseases. In: Kaufman DW, Kelly JP, Levy M, Shapiro S (eds) The drug etiology of agranulocytosis and aplastic anemia. Oxford University Press, New York/Oxford, pp 27–53
Dunk LR, Annan LJ, Andrews CD (2006) Rechallenge with clozapine following leucopenia or neutropenia during previous therapy. Br J Psychiatry 188:255–263
Netherlands Clozapine Collaboration Group (2009) Guideline for the use of clozapine. http://www.clozapinepluswerkgroep.nl
Kanaan RA, Kerwin RW (2006) Lithium and clozapine rechallenge: a retrospective case analysis. J Clin Psychiatry 67:756–760
Conflict of interest
J. Bogers has no financial or other conflicting relationships. D. Cohen has received a grant from Eli-Lilly and Janssen and honoraria from Astra-Zeneca, Bristol-Myers-Squibb and Eli-Lilly. P. Schulte has received honoraria from Astra-Zeneca, Bristol-Myers-Squibb and Eli-Lilly. D. van Dijk has received a grant from Eli-Lilly. B. Bakker has no financial or other conflicting relationships.
Author information
Authors and Affiliations
Corresponding author
Additional information
The authors are members of the board of the Netherlands Clozapine Collaboration Group.
Rights and permissions
About this article
Cite this article
Bogers, J.P.A.M., Cohen, D., Schulte, P.F.J. et al. Clozapine-induced leukopenia: arguments for rechallenge. Ir J Med Sci 181, 155–156 (2012). https://doi.org/10.1007/s11845-011-0782-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11845-011-0782-5