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First Irish birth following IVF therapy using antagonist protocol

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Abstract

Background

During in vitro fertilization (IVF), the prevention of a premature LH surge was traditionally achieved using a gonadotrophin releasing hormone agonist (GnRH-a), and more recently, a GnRH antagonist.

Aims

We report a case of a 37 year old treated using the GnRH antagonist in a second completed cycle of IVF.

Methods

IVF was performed for primary infertility of 5-year duration due to frozen pelvis secondary to endometriosis.

Results

Following controlled ovarian hyperstimulation, oocyte recovery and fertilization, cleavage and transfer of two zygotes, a pregnancy established. A twin gestation was diagnosed at 7-weeks scan and pregnancy ended with the delivery of twin girls by emergency caesarean section.

Conclusion

This is a first report of a delivery following IVF using the antagonist protocol in Ireland. Such therapy is patient friendly and its use should be introduced on a larger scale in clinical practice.

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Correspondence to E. V. Mocanu.

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Mocanu, E.V., Kondaveeti, N., Kelly, J. et al. First Irish birth following IVF therapy using antagonist protocol. Ir J Med Sci 179, 455–457 (2010). https://doi.org/10.1007/s11845-009-0336-2

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  • DOI: https://doi.org/10.1007/s11845-009-0336-2

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