Skip to main content
Log in

High prevalence of vitamin D insufficiency in healthy Irish adults

  • Original Article
  • Published:
Irish Journal of Medical Science Aims and scope Submit manuscript

Abstract

Background

Specific sub-groups of the population, such as older people, are at increased risk of poor vitamin D status. There is growing evidence, however, that vitamin D insufficiency may be a more widespread problem.

Aim

To determine the prevalence of vitamin D insufficiency in a group of healthy Irish adults.

Methods

Serum 25-hydroxyvitamin D was measured by radioimmunoassay in 70 healthy Irish adults working in South Dublin.

Results

Overall, half of the group (51%) had vitamin D insufficiency; this was more pronounced in wintertime, with prevalence rising to 58%. Winter was a significant negative predictor of serum 25-OH D levels. Sixteen percent of the participants reported taking a vitamin D-containing supplement (multivitamin), but this did not significantly influence the serum 25-OH D levels.

Conclusion

Vitamin D insufficiency is not confined to “at-risk groups” and is likely to be prevalent in the general public in Ireland, especially in wintertime.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Food-Safety-Authority-of-Ireland (2007) Recommendations for a National policy on vitamin D supplementation for infants in Ireland

  2. McCarthy D, Collins A, O’Brien M, Lamberg-Allardt C, Jakobsen J, Charzewska J et al (2006) Vitamin D intake and status in Irish elderly women and adolescent girls. Ir J Med Sci 175:14–20

    Article  PubMed  CAS  Google Scholar 

  3. Hill T, O’Brien M, Lamberg-Allardt C, Jakobsen J, Kiely M, Flynn A et al (2006) Vitamin D status of 51–75-year-old Irish women: its determinants and impact on biochemical indices of bone turnover. Public Health Nutr 9(2):225–233

    Article  PubMed  Google Scholar 

  4. Chapuy MC, Preziosi P, Maamer M, Arnaud S, Galan P, Hercberg S et al (1997) Prevalence of vitamin D insufficiency in an adult normal population. Osteoporos Int 7(5):439–443

    Article  PubMed  CAS  Google Scholar 

  5. Hypponen E, Power C (2007) Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors. Am J Clin Nutr 85(3):860–868

    PubMed  CAS  Google Scholar 

  6. Lips P (2004) Which circulating level of 25-hydroxyvitamin D is appropriate? J Steroid Biochem Mol Biol 89–90:611–614

    Article  PubMed  CAS  Google Scholar 

  7. Heaney R (2004) Functional indices of vitamin D status and ramifications of vitamin D deficiency. Am J Clin Nutr 80(6):1706S–1709S

    PubMed  CAS  Google Scholar 

  8. Vieth R, Carter G (2001) Difficulties with vitamin D nutrition research: objective targets of adequacy, and assays for 25-hydroxyvitamin D. Eur J Clin Nutr 55(4):221–222

    Article  PubMed  CAS  Google Scholar 

  9. The Irish Osteoporosis Society. http://www.irishosteoporosis.ie

  10. Holick MF (2005) The vitamin D epidemic and its health consequences. J Nutr 135(11):2739S–2748S

    PubMed  CAS  Google Scholar 

  11. Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M et al (2007) Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis. Am J Prev Med 32(3):210–216

    Article  PubMed  Google Scholar 

  12. Central-Statistics-Office. Government of Ireland CSO Census, Principal Socio-Economic Results 2003

  13. Javaid MK, Crozier SR, Harvey NC, Gale CR, Dennison EM, Boucher BJ et al (2006) Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study. Lancet 367(9504):36–43

    Article  PubMed  CAS  Google Scholar 

  14. McCarthy D, Duggan P, O’Brien M, Kiely M, McCarthy J, Shanahan F et al (2005) Seasonality of vitamin D status and bone turnover in patients with Crohn’s disease. Aliment Pharmacol Ther 21(9):1073–1083

    Article  PubMed  CAS  Google Scholar 

  15. Scott E, Gaywood I, Scott B (2000) Guidelines for osteoporosis in coeliac disease and inflammatory bowel disease. Gut 46(Suppl 1):1–8

    Article  Google Scholar 

  16. Webb A, Kline L, Holick M (1988) Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not provide vitamin D3 synthesis in human skin. J Clin Endocrinol Metab 67:373–378

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgment

This study was funded by the Meath Foundation, Dublin (http://www.meathfoundation.com).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M. O’Sullivan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

O’Sullivan, M., Nic Suibhne, T., Cox, G. et al. High prevalence of vitamin D insufficiency in healthy Irish adults. Ir J Med Sci 177, 131–134 (2008). https://doi.org/10.1007/s11845-008-0129-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11845-008-0129-z

Keywords

Navigation