Skip to main content
SpringerLink
Log in

Leg bone pain syndrome in a patient with ulcerative colitis treated with cyclosporin

  • Case Report
  • Published:
Irish Journal of Medical Science Aims and scope Submit manuscript

Abstract

Background

Leg bone pain syndrome is an unusual condition associated with the use of calcineurin antagonists, initially described in patients receiving allograft transplantation.

Aim

To describe the first known reported case of leg bone pain syndrome in a patient with ulcerative colitis receiving cyclosporin.

Results

Investigations revealed no diagnostic features. Calcium channel blocker was used successfully in the treatment of this condition.

Conclusion

In the absence of diagnostic investigations, a high index of clinical suspicion is needed to diagnose and successfully manage leg bone pain syndrome. This may prevent further complications such as osteonecrosis that may arise.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Gauthier VJ, Barbosa LM (1994) Bone pain in transplant recepients responsive to calcium channel blockers. Ann Int Med 121:863–865

    PubMed  CAS  Google Scholar 

  2. Villaverde V, Cantalejo M, Balsa A, Mola EM (1999) Leg bone pain syndrome in a kidney transplant patient treated with tacrolimus (FK506) (Correspondence). Ann Rheum Dis 58:653–654

    Article  PubMed  CAS  Google Scholar 

  3. Isaacs K (1998) Severe bone pain as an adverse effect of cyclosporin therapy for Crohn’s disease. Inflamm Bowel Dis 4:95–97

    Article  PubMed  CAS  Google Scholar 

  4. Lawson CA, Fraser A, Veale DJ, Emery P (2003) Cyclosporin treatment in psoriatic arthritis: a cause of severe leg pain. Ann Rheum Dis 62:489

    Article  PubMed  CAS  Google Scholar 

  5. Ybarra J, Crespo M, Torregrosa JV, Fuster D, Campistol JM (2003) Oppenheimer F. Reflex sympathetic dystrophy syndrome in renal transplanted patients under immunosuppression with tacrolimus. Transplant Proc 35:2937–2939

    Article  PubMed  CAS  Google Scholar 

  6. Thami GP, Bhalla M (2003) Erythromelalgia induced by possible calcium channel blockade by cyclosporin. BMJ 326:910

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Gastroenterology, Beaumont Hospital, Beaumont, Dublin, Ireland

    A. H. Abdul Rahman, C. O’Brien & S. E. Patchett

Authors
  1. A. H. Abdul Rahman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. O’Brien
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. E. Patchett
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. H. Abdul Rahman.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rahman, A.H.A., O’Brien, C. & Patchett, S.E. Leg bone pain syndrome in a patient with ulcerative colitis treated with cyclosporin. Ir J Med Sci 176, 129–131 (2007). https://doi.org/10.1007/s11845-007-0024-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11845-007-0024-z

Keywords

Search

Navigation