Skip to main content
Log in

Surpoids, obésité : quel impact sur la récidive du cancer du sein ?

Influence of overweight and obesity on breast cancer survival

  • Article Original / Original Article
  • Published:
Psycho-Oncologie

Résumé

En plus de son rôle de facteur de risque du cancer du sein après la ménopause, l’obésité a été associée à un moins bon pronostic du cancer du sein. Cependant, le niveau de preuve de cette association n’est pas encore satisfaisant, car les études sur le sujet présentent des différences méthodologiques importantes. Cet article a donc pour objectif de réaliser un état de l’art des relations entre obésité et survie après cancer du sein.

Abstract

Obesity is a well-known risk factor for postmenopausal breast cancer. It has also been associated with poor prognosis of breast cancer. However, existing evidence regarding the association of obesity and breast cancer prognosis is not sufficient, since methodological differences exist between studies. The aim of this article is to review relationships between overweight and obesity, and survival after breast cancer.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Références

  1. Binder-Foucard F, Belot A, Delafosse P, et al (2013) National estimate of the incidence and mortality from cancer in France between 1980 and 2012. Part 1 — Solid tumors. Institut de veille sanitaire, Saint-Maurice

    Google Scholar 

  2. Cowppli-Bony A, Uhry Z, Remontet L, et al (2016) Survie des personnes atteintes de cancer en France 1989–2013. Partie 1 — Tumeurs solides. Institut de veille sanitaire, Saint-Maurice

    Google Scholar 

  3. Dartois L, Fagherazzi G, Baglietto L, et al (2016) Proportion of premenopausal and postmenopausal breast cancers attributable to known risk factors: estimates from the E3N–EPIC cohort. Int J Cancer 138:2415–27

    Article  PubMed  Google Scholar 

  4. World Cancer Research Fund, American Institute for Cancer Research (2010) Breast Cancer 2010 Report. Food, Nutrition, Physical Activity and the Prevention of Breast Cancer. AICR, Washington

    Google Scholar 

  5. INCa (2015) Nutrition et prévention primaire des cancers: actualisation des données. Coll. « État des lieux et des connaissances »

    Google Scholar 

  6. Parekh N, Chandran U, Bandera EV (2012) Obesity in cancer survival. Annu Rev Nutr 32:311–42

    Article  PubMed  Google Scholar 

  7. World Cancer Research Fund International, American Institute for Cancer Research (2014) Continuous Update Project Report: diet, nutrition, physical activity, and breast cancer survivors

  8. Abe R, Kumagai N, Kimura M, et al (1976) Biological characteristics of breast cancer in obesity. Tohoku J Exp Med 120:351–9

    Article  PubMed  Google Scholar 

  9. Goodwin PJ, Boyd NF (1990) Body size and breast cancer prognosis: a critical review of the evidence. Breast Cancer Res Treat 16:205–14

    Article  PubMed  Google Scholar 

  10. Azrad M, Demark-Wahnefried W (2014) The association between adiposity and breast cancer recurrence and survival: a review of the recent literature. Curr Nutr Rep 3:9–15

    Article  PubMed  PubMed Central  Google Scholar 

  11. Carmichael AR (2006) Obesity and prognosis of breast cancer. Obes Rev 7:333–40

    Article  PubMed  Google Scholar 

  12. Chan DS, Vieira AR, Aune D, et al (2014) Body mass index and survival in women with breast cancer-systematic literature review and meta-analysis of 82 follow-up studies. Ann Oncol 25:1901–14

    Article  PubMed  PubMed Central  Google Scholar 

  13. Druesne-Pecollo N, Touvier M, Barrandon E, et al (2012) Excess body weight and second primary cancer risk after breast cancer: a systematic review and meta-analysis of prospective studies. Breast Cancer Res Treat 135:647–54

    Article  PubMed  Google Scholar 

  14. Hauner D, Janni W, Rack B, Hauner H (2011) The effect of overweight and nutrition on prognosis in breast cancer. Dtsch Arztebl Int 108:795–801

    PubMed  PubMed Central  Google Scholar 

  15. McTiernan A, Irwin M, Vongruenigen V (2010) Weight, physical activity, diet, and prognosis in breast and gynecologic cancers. J Clin Oncol 28:4074–80

    Article  PubMed  PubMed Central  Google Scholar 

  16. Niraula S, Ocana A, Ennis M, Goodwin PJ (2012) Body size and breast cancer prognosis in relation to hormone receptor and menopausal status: a meta-analysis. Breast Cancer Res Treat 134:769–81

    Article  PubMed  Google Scholar 

  17. Patterson RE, Cadmus LA, Emond JA, Pierce JP (2010) Physical activity, diet, adiposity and female breast cancer prognosis: a review of the epidemiologic literature. Maturitas 66:5–15

    Article  PubMed  Google Scholar 

  18. Protani M, Coory M, Martin JH (2010) Effect of obesity on survival of women with breast cancer: systematic review and metaanalysis. Breast Cancer Res Treat 123:627–35

    Article  PubMed  Google Scholar 

  19. Ryu SY, Kim CB, Nam CM, et al (2001) Is body mass index the prognostic factor in breast cancer: a meta-analysis. J Korean Med Sci 16:610–4

    Article  PubMed  PubMed Central  Google Scholar 

  20. Sinicrope FA, Dannenberg AJ (2011) Obesity and breast cancer prognosis: weight of the evidence. J Clin Oncol 29:4–7

    Article  PubMed  Google Scholar 

  21. Vance V, Mourtzakis M, McCargar L, Hanning R (2011) Weight gain in breast cancer survivors: prevalence, pattern and health consequences. Obes Rev 12:282–94

    Article  PubMed  Google Scholar 

  22. Gourgou-Bourgade S, Cameron D, Poortmans P, et al (2015) Guidelines for time-to-event endpoint definitions in Breast cancer trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials). Ann Oncol 26:873–9

    Article  PubMed  Google Scholar 

  23. Hudis CA, Barlow WE, Costantino JP, et al (2007) Proposal for standardized definitions for efficacy end points in adjuvant breast cancer trials: the STEEP system. J Clin Oncol 25:2127–32

    Article  PubMed  Google Scholar 

  24. His M, Fagherazzi G, Mesrine S, et al (2016) Pre-diagnostic body size and breast cancer survival in the E3N cohort study. Int J Cancer 139:1053–64

    Article  PubMed  Google Scholar 

  25. Kwan ML, John EM, Caan BJ, et al (2014) Obesity and mortality after breast cancer by race/ethnicity: the California Breast Cancer Survivorship Consortium. Am J Epidemiol 179:95–111

    Article  PubMed  Google Scholar 

  26. Reichle K, Peter RS, Concin H, Nagel G (2015) Associations of pre-diagnostic body mass index with overall and cancer-specific mortality in a large Austrian cohort. Cancer Causes Control 26:1643–52

    Article  PubMed  Google Scholar 

  27. Shariff-Marco S, Gomez SL, Sangaramoorthy M, et al (2015) Impact of neighborhoods and body size on survival after breast cancer diagnosis. Health Place 36:162–72

    Article  PubMed  Google Scholar 

  28. Kwan ML, Chen WY, Kroenke CH, et al (2012) Pre-diagnosis body mass index and survival after breast cancer in the after Breast Cancer Pooling Project. Breast Cancer Res Treat 132:729–39

    Article  PubMed  Google Scholar 

  29. Kamineni A, Anderson ML, White E, et al (2013) Body mass index, tumor characteristics, and prognosis following diagnosis of early-stage breast cancer in a mammographically screened population. Cancer Causes Control 24:305–12

    Article  PubMed  Google Scholar 

  30. Loi S, Milne RL, Friedlander ML, et al (2005) Obesity and outcomes in premenopausal and postmenopausal breast cancer. Cancer Epidemiol Biomarkers Prev 14:1686–91

    Article  PubMed  Google Scholar 

  31. Caan BJ, Kwan ML, Hartzell G, et al (2008) Pre-diagnosis body mass index, post-diagnosis weight change, and prognosis among women with early-stage breast cancer. Cancer Causes Control 19:1319–28

    Article  PubMed  PubMed Central  Google Scholar 

  32. Kroenke CH, Chen WY, Rosner B, Holmes MD (2005) Weight, weight gain, and survival after breast cancer diagnosis. J Clin Oncol 23:1370–8

    Article  PubMed  Google Scholar 

  33. Nelson SH, Marinac CR, Patterson RE, et al (2016) Impact of very low physical activity, BMI, and comorbidities on mortality among breast cancer survivors. Breast Cancer Res Treat 155:551–7

    Article  PubMed  Google Scholar 

  34. Scholz C, Andergassen U, Hepp P, et al (2015) Obesity as an independent risk factor for decreased survival in node-positive high-risk breast cancer. Breast Cancer Res Treat 151:569–76

    Article  PubMed  Google Scholar 

  35. Sun X, Nichols HB, Robinson W, et al (2015) Post-diagnosis adiposity and survival among breast cancer patients: influence of breast cancer subtype. Cancer Causes Control 26:1803–11

    Article  PubMed  Google Scholar 

  36. Copson ER, Cutress RI, Maishman T, et al (2015) Obesity and the outcome of young breast cancer patients in the UK: the POSH study. Ann Oncol 26:101–12

    Article  PubMed  Google Scholar 

  37. Pan H, Gray RG, Early Breast Cancer Trialists’ Collaborative Group (2014) Effect of obesity in premenopausal ER+ early breast cancer: EBCTCG data on 80,000 patients in 70 trials. J Clin Oncol 32:5s [suppl; abstr 503]

    Article  Google Scholar 

  38. Nechuta S, Chen WY, Cai H, et al (2016) A pooled analysis of post-diagnosis lifestyle factors in association with late estrogenreceptor- positive breast cancer prognosis. Int J Cancer 138:2088–97

    Article  PubMed  Google Scholar 

  39. Dal Maso L, Zucchetto A, Talamini R, et al (2008) Effect of obesity and other lifestyle factors on mortality in women with breast cancer. Int J Cancer 123:2188–94

    Article  Google Scholar 

  40. Majed B, Moreau T, Senouci K, et al (2008) Is obesity an independent prognosis factor in woman breast cancer? Breast Cancer Res Treat 111:329–42

  41. Senie RT, Rosen PP, Rhodes P, et al (1992) Obesity at diagnosis of breast carcinoma influences duration of disease-free survival. Ann Intern Med 116:26–32

    Article  PubMed  Google Scholar 

  42. Harding JL, Shaw JE, Anstey KJ, et al (2015) Comparison of anthropometric measures as predictors of cancer incidence: a pooled collaborative analysis of 11 Australian cohorts. Int J Cancer 137:1699–708

    Article  PubMed  Google Scholar 

  43. World Cancer Research Fund International, American Institute for Cancer Research (2014) Continuous update project report: systematic review on diet, nutrition, physical activity and survival and second cancers in breast cancer survivors

    Google Scholar 

  44. Zhang S, Folsom AR, Sellers TA, et al (1995) Better breast cancer survival for postmenopausal women who are less overweight and eat less fat. The Iowa Women’s Health Study. Cancer 76:275–83

    PubMed  Google Scholar 

  45. Borugian MJ, Sheps SB, Kim-Sing C, et al (2003) Waist-to-hip ratio and breast cancer mortality. Am J Epidemiol 158:963–8

    Article  PubMed  Google Scholar 

  46. George SM, Bernstein L, Smith AW, et al (2014) Central adiposity after breast cancer diagnosis is related to mortality in the health, eating, activity, and lifestyle study. Breast Cancer Res Treat 146:647–55

    Article  PubMed  Google Scholar 

  47. Abrahamson PE, Gammon MD, Lund MJ, et al (2006) General and abdominal obesity and survival among young women with breast cancer. Cancer Epidemiol Biomarkers Prev 15:1871–7

    Article  PubMed  Google Scholar 

  48. Goodwin PJ, Ennis M, Pritchard KI, et al (2012) Insulin- and obesity-related variables in early-stage breast cancer: correlations and time course of prognostic associations. J Clin Oncol 30:164–71

    Article  PubMed  Google Scholar 

  49. Playdon MC, Bracken MB, Sanft TB, et al (2015) Weight gain after breast cancer diagnosis and all-cause mortality: systematic review and meta-analysis. J Natl Cancer Inst 107:djv275

    Article  PubMed  Google Scholar 

  50. Chan DS, Norat T (2015) Obesity and breast cancer: not only a risk factor of the disease. Curr Treat Options Oncol 16:22

    Article  PubMed  Google Scholar 

  51. Chlebowski RT, Blackburn GL, Thomson CA, et al (2006) Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women’s Intervention Nutrition Study. J Natl Cancer Inst 98:1767–76

    Article  PubMed  Google Scholar 

  52. Pierce JP, Natarajan L, Caan BJ, et al (2007) Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women’s Healthy Eating and Living (WHEL) randomized trial. JAMA 298:289–98

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to M. His, F. Clavel-Chapelon or L. Dossus.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

His, M., Clavel-Chapelon, F. & Dossus, L. Surpoids, obésité : quel impact sur la récidive du cancer du sein ?. Psycho Oncologie 10, 193–199 (2016). https://doi.org/10.1007/s11839-016-0585-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11839-016-0585-z

Mots clés

Keywords

Navigation