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Green Synthesis of Magnesium Oxide Nanoparticles with Antioxidant Potential Using the Leaf Extract of Piper nigrum

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Abstract

Green fabrication is an environmentally friendly and innovative method, and an attractive research field for the production of magnesium oxide nanoparticles (MgO NPs) in clinical and environmental applications. In this study, a viable green synthetic approach has been carried out to produce MgO NPs by using leaf aqueous extract of Piper nigrum as a capping agent. The formation and physicochemical properties of the MgO NPs were confirmed through standard characterization methods. All the analytical data revealed the formation of pure, rod-shaped, and crystalline MgO NPs with an average size of 20 nm. The low concentration of 50 µg/mL MgO NPs shows 29.99% free radical scavenging, whereas the highest concentration of 500 µg/mL MgO NPs exhibits 91.99% free radical scavenging compared with ascorbic acid. The IC50 of the MgO NPs was found to be 89.5 µg/mL. This study shows that the synthesized MgO NPs exhibit good anti-oxidant activity that can be used for biomedical applications.

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Acknowledgements

The authors thank the Karpagam Academy of Higher Education for providing the laboratory facilities to conduct the experiments and the authors acknowledge the DST-FIST for supporting the infrastructure facility (SR/FST/LS-1/2018/187).

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Authors and Affiliations

  1. Department of Biotechnology, Karpagam Academy of Higher Education, Coimbatore, Tamil Nadu, 641021, India

    Rajiv Periakaruppan & V. Naveen

  2. Centre for Ocean Research (DST-FIST Sponsored Centre), MoES - Earth Science and Technology Cell (Marine Biotechnological Studies), Sathyabama Institute of Science and Technology, Col. Dr. Jeppiaar Research Park, Chennai, Tamil Nadu, 600 119, India

    Jeyapragash Danaraj

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  1. Rajiv Periakaruppan
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  2. V. Naveen
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  3. Jeyapragash Danaraj
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Contributions

PR: Supervision, Funding acquisition and Project administration. NV: Investigation, Methodology, Data Curation and Writing- Original draft preparation. JD: Data Curation and Writing.

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Correspondence to Rajiv Periakaruppan.

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Periakaruppan, R., Naveen, V. & Danaraj, J. Green Synthesis of Magnesium Oxide Nanoparticles with Antioxidant Potential Using the Leaf Extract of Piper nigrum. JOM 74, 4817–4822 (2022). https://doi.org/10.1007/s11837-022-05548-x

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