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Cyrtrandroemia nicobarica-Synthesized ZnO NRs: A New Tool in Cancer Treatment

JOM volume 73, pages 364–372 (2021)Cite this article

Abstract

There has been a developing interest in the green-mediated synthesis of metal nanorods (NRs), especially from plants. However, there is no published report on the synthesis of ZnO NRs prepared via Cyrtrandroemia nicobarica leaf extract. The formation of ZnO NRs was confirmed by using x-ray diffraction, a Fourier transform infrared spectrometer, Brunauer–Emmett–Teller analysis, scanning electron microscope-energy-dispersive x-ray spectroscopy, and transmission electron microscopy analyses. The result revealed that the acquired ZnO NRs contain a unique surface area and excellent particle size. The photocatalytic and antioxidant activities of ZnO NRs were also evaluated in this study. The toxic nature of the obtained ZnO NRs was analyzed using the Daniorerio model, and the results showed that it was nontoxic. The anticancer activity of ZnO NRs was also analyzed using a human lung cancer cell line (A549), and excellent results were observed about the cancer cell death pathway. Hence, it was confirmed that the acquired ZnO NRs were nontoxic and had magnificent antibacterial and antioxidant activities. They can be used as an anticancer drug for health-care implementations.

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Acknowledgements

The authors thank the management of K. S. Rangasamy College of Arts and Science (Autonomous), Tiruchengode, Tamil Nadu, for their support and encouragement.

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Authors and Affiliations

  1. Department of Biotechnology, K. S. Rangasamy College of Arts and Science (Autonomous), Tiruchengode, Tamil Nadu, 637215, India

    Kattakgoundar Govindaraj Sudha, Saheb Ali, Mariyappan Kowsalya & Mohan Prasanna Rajeshkumar

  2. Biosensor Research Institute, Department of Fine Chemistry, Seoul National University of Science and Technology, Gongneung-ro 232, Nowon-Gu, Seoul, 01811, Republic of Korea

    Gopalu Karunakaran

  3. Department of Functional Nanosystems and High-Temperature Materials, National University of Science and Technology “MISiS”, Leninskiy Pr. 4, Moscow, 119049, Russia

    Evgeny Kolesnikov

  4. Department of Physical Materials Science, National University of Science and Technology “MISiS”, Leninskiy Pr. 4, Moscow, 119049, Russia

    Mikhail V. Gorshenkov

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  1. Kattakgoundar Govindaraj Sudha
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Sudha, K.G., Ali, S., Karunakaran, G. et al. Cyrtrandroemia nicobarica-Synthesized ZnO NRs: A New Tool in Cancer Treatment. JOM 73, 364–372 (2021). https://doi.org/10.1007/s11837-020-04486-w

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  • DOI: https://doi.org/10.1007/s11837-020-04486-w