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Peptides natriurétiques en biologie clinique: quelques applications particulières

Natriuretic peptides in clinical biology: a few specific applications

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BioTribune Magazine

Résumé

La compréhension du rôle cardiaque des hormones natriurétiques est récente (BNPet NT pro-BNP). Le niveau plasmatique des peptides natriurétiques est bien corrélé à la sévérité des dysfonctions cardiaques (classification NYHA). Nous présentons dans cet article l’intérêt du dosage des peptides natriurétiques dans plusieurs indications médicales: maladies du sang, oncologie, diabète, sport-santé et psychiatrie. Les peptides natriurétiques peuvent être des marqueurs biologiques utiles en pratique clinique chez les patients suspects de défaillance cardiaque dans ces situations particulières.

Abstract

Knowledge of the cardiac role played by natriuretic peptides is recent (BNP and NT pro-BNP). The plasma levels of these natriuretic peptides are well correlated with the severity of cardiac dysfunction (NYHA classification). We outline the interest of natriuretic peptides in several medical indications: blood diseases, oncology, diabetes, sport health and psychiatry. Natriuretic peptides could prove to be useful biomarkers in clinical practice for patients with suspected heart failure in these specific situations.

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Authors and Affiliations

  1. Pôle Santé et Biotechnologie, École Centrale de Paris, Grande Voie des Vignes, 92295, Chatenay-Malabry cedex, France

    G. Dine

  2. Institut biotechnologique de Troyes, 11, rue Marie-Curie, 10000, Troyes, France

    G. Dine, V. Genty & Y. Rehn

Authors
  1. G. Dine
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  2. V. Genty
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  3. Y. Rehn
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Correspondence to G. Dine.

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Dine, G., Genty, V. & Rehn, Y. Peptides natriurétiques en biologie clinique: quelques applications particulières. Bio trib. mag. 23, 19–22 (2007). https://doi.org/10.1007/s11834-007-0016-3

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  • DOI: https://doi.org/10.1007/s11834-007-0016-3

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