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Surgical synovectomy of the knee in young haemophiliacs: long-term results of a monocentric series of 23 patients

  • Original Clinical Article
  • Published:
Journal of Children's Orthopaedics

Abstract

Background

In haemophiliacs, synovectomy is indicated for recurrent joint bleedings, despite medical treatment.

Method

We report a series of 23 surgical synovectomies of the knee with a median follow-up of 8.8 years. The median age of patients at surgery was 13.5 years. Clinical and radiological evaluations were made according to the Petrini and the Pettersson scores, at 1 and 5 years after surgery, and at the last follow-up. Wilcoxon and Spearman’s tests were used for the statistical analysis.

Result

The Petrini score improved at 1 and 5 years (P < 0.001). Nine patients have 20 years of follow-up and a stable result. In more than half of the knees, no episode of recurrent bleeding occurred. The effect of surgery on the range of motion (ROM) was moderate and mobilisation under anaesthesia did not improve it significantly. There was a progressive worsening of the radiological score, but no correlation between clinical and radiological score was noticed (ρ = 0.08, P = 0.77).

Conclusion

Complete synovectomy gives good long-term results in term of bleeding recurrence and overall function.

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References

  1. Pergantou H, Matsinos G, Papadopoulos A, Platokouki H, Aronis S (2006) Comparative study of validity of clinical, X-ray and magnetic resonance imaging scores in evaluation and management of haemophilic arthropathy in children. Haemophilia 12:241–247

    Article  CAS  Google Scholar 

  2. Thomason HC 3rd, Wilson FC, Lachiewicz PF, Kelley SS (1999) Knee arthroplasty in hemophilic arthropathy. Clin Orthop Relat Res 360:169–173

    Article  Google Scholar 

  3. Rodriguez-Merchan EC, Wiedel JD (2001) General principles and indications of synoviorthesis (medical synovectomy) in haemophilia. Haemophilia 7(Suppl 2):6–10

    Article  Google Scholar 

  4. Figgie MP, Goldberg VM, Figgie HE 3rd, Heiple KG, Sobel M (1989) Total knee arthroplasty for the treatment of chronic hemophilic arthropathy. Clin Orthop Relat Res 248:98–107

    Google Scholar 

  5. Vastel L, Courpied JP, Sultan Y, Kerboull M (1999) Arthroplastie totale du genou chez l’hémophile. Rev Chir Orthop Reparatrice Appar Mot 85(5):458–465

    CAS  Google Scholar 

  6. Bae DK, Yoon KH, Kim HS, Song SJ (2005) Total knee arthroplasty in hemophilic arthropathy of the knee. J Arthroplasty 20(5):664–668

    Article  Google Scholar 

  7. Silva M, Luck JV Jr (2005) Long-term results of primary total knee replacement in patients with hemophilia. J Bone Joint Surg Am 87(1):85–91

    Article  Google Scholar 

  8. Sheth DS, Oldfield D, Ambrose C, Clyburn T (2004) Total knee arthroplasty in hemophilic arthropathy. J Arthroplasty 19(1):56–60

    Article  Google Scholar 

  9. Solimeno LP, Mancuso ME, Pasta G, Santagostino E, Perfetto S, Mannucci PM (2009) Factors influencing the long-term outcome of primary total knee replacement in haemophiliacs: a review of 116 procedures at a single institution. Br J Haematol 145:227–234

    Article  Google Scholar 

  10. Storti E, Traldi A, Tosatti E, Davoli PG (1969) Synovectomy, a new approach to haemophilic arthropathy. Acta Haematol 41:193–205

    Article  CAS  Google Scholar 

  11. Triantafyllou SJ, Hanks GA, Handal JA, Greer RB 3rd (1992) Open and arthroscopic synovectomy in hemophilic arthropathy of the knee. Clin Orthop Relat Res 283:196–204

    Google Scholar 

  12. Montane I, McCollough NC 3rd, Lian EC (1986) Synovectomy of the knee for hemophilic arthropathy. J Bone Joint Surg Am 68(2):210–216

    CAS  Google Scholar 

  13. Wiedel JD (1996) Arthroscopic synovectomy of the knee in hemophilia: 10-to-15 year followup. Clin Orthop Relat Res 328:46–53

    Article  Google Scholar 

  14. Van den Berg HM, Dunn A, Fischer K, Blanchette VS (2006) Prevention and treatment of musculoskeletal disease in the haemophilia population: role of prophylaxis and synovectomy. Haemophilia 12(Suppl 3):159–168

    Article  Google Scholar 

  15. Hill FGH, Ljung R (2003) Third and fourth Workshops of the European Paediatric Network for Haemophilia Management. Haemophilia 9:223–228

    Article  CAS  Google Scholar 

  16. Pettersson H, Ahlberg A, Nilsson IM (1980) A radiologic classification of hemophilic arthropathy. Clin Orthop Relat Res 149:153–159

    Google Scholar 

  17. Herring JA (2007) Chapter 36. Hematologic disorders. In: Herring JA (ed) Tachdjian’s pediatric orthopaedics, 4th edn, vol 2. Saunders Elsevier, Philadelphia, PA, pp 2167–2169

    Google Scholar 

  18. Arnold WD, Hilgartner MW (1977) Hemophilic arthropathy. Current concepts of pathogenesis and management.. J Bone Joint Surg Am 59(3):287–305

    CAS  Google Scholar 

  19. Le Balch T, Girard F, Chaix O, Françoy P, Jouanin T, Mazas F (1987) La synovectomie arthroscopique du genou chez l’hémophile. Rev Chir Orthop Reparatrice Appar Mot 73(Suppl II):122–125

    Google Scholar 

  20. Tamurian RM, Spencer EE, Wojtys EM (2002) The role of arthroscopic synovectomy in the management of hemarthrosis in hemophilia patients: financial perspectives. Arthroscopy 18(7):789–794

    Article  Google Scholar 

  21. Dunn AL, Busch MT, Wyly JB, Sullivan KM, Abshire TC (2004) Arthroscopic synovectomy for hemophilic joint disease in a pediatric population. J Pediatr Orthop 24(4):414–426

    Article  Google Scholar 

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Correspondence to Virginie Rampal.

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Rampal, V., Odent, T., Torchet, M.F. et al. Surgical synovectomy of the knee in young haemophiliacs: long-term results of a monocentric series of 23 patients. J Child Orthop 4, 33–37 (2010). https://doi.org/10.1007/s11832-009-0229-y

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  • DOI: https://doi.org/10.1007/s11832-009-0229-y

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