Zusammenfassung
Am Beispiel der Muskeldystrophie Duchenne werden Risikoberechnungen beim X-chromosomal rezessiven Erbgang mithilfe des Bayesschen Rechentableaus durchgeführt und dabei demonstriert, wie sich auch komplexe genetische Modelle berücksichtigen lassen und auf das Risiko auswirken.
Abstract
Using the example of Duchenne muscular dystrophy, risk calculations for X-linked recessive traits are performed using the Bayesian computation tableaus, demonstrating how to take even complex genetic models and their impact on the calculated risk into consideration.
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Grimm, T., Fischer, C. Risikoberechnungen beim X-chromosomal rezessiven Erbgang. medgen 23, 373–376 (2011). https://doi.org/10.1007/s11825-011-0294-8
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DOI: https://doi.org/10.1007/s11825-011-0294-8