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Schlaf, Plastizität und Gedächtnis

  • H. Piosczyk
  • C. Kloepfer
  • D. Riemann
  • C. NissenEmail author
Originalien

Zusammenfassung

Zahlreiche Untersuchungen – von der molekularen bis zur Verhaltensebene – zeigen, dass gesunder Schlaf neuronale Plastizität und die damit verbundene Konsolidierung deklarativen und prozeduralen Gedächtnisses begünstigt. Der vorliegende Artikel gibt einen Überblick über die aktuellen grundlagenwissenschaftlichen und klinischen Befunde. Die Ergebnisse der Schlafforschung sind dabei nicht nur für Grundlagenfragen zu Plastizität und Gedächtnisbildung interessant. Aus klinischer Perspektive können diese Erkenntnisse für gesundheitspolitisch wichtige Bereiche, wie empfehlenswertes Schlaf- und Lernverhalten, informativ sein. Weiterhin können die sich abzeichnenden Veränderungen der Gedächtnisbildung bei Patienten mit gestörtem Schlaf, wie bei primärer Insomnie oder zahlreichen psychischen Erkrankungen, zu einem vollständigeren Verständnis dieser Erkrankungen beitragen. Das langfristige Ziel ist, hieraus Ratschläge zu gesundem Verhalten und neue Behandlungsvorschläge für Patienten mit gestörtem Schlaf oder geminderter Gedächtnisfunktion abzuleiten.

Schlüsselwörter

Schlaf Gedächtnis Plastizität Deklarativ Prozedural Funktion von Schlaf Schlafstörung 

Sleep, plasticity and memory

Abstract

A compelling line of evidence – from the molecular to the behavioural level – indicates that healthy sleep facilitates neural plasticity and related declarative and procedural memory consolidation. This review provides an overview of the current basic research and clinical findings. Emerging insights into the interplay between sleep and memory have the potential to be informative for fundamental processes of brain plasticity. From a clinical perspective, new findings of disrupted sleep-related memory under conditions of disturbed sleep, such as in primary insomnia or many mental illnesses, may contribute to a more complete understanding of the disorders. The long-term goal of this research includes recommendations on healthy behavioural patterns and the development of novel interventional strategies for patients with disturbed sleep or reduced memory function.

Keywords

Sleep Memory Plasticity Declarative Procedural Function of sleep Sleep disorder 

Notes

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

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Copyright information

© Springer 2009

Authors and Affiliations

  • H. Piosczyk
    • 1
  • C. Kloepfer
    • 1
  • D. Riemann
    • 1
  • C. Nissen
    • 1
    Email author
  1. 1.Abteilung für Psychiatrie und PsychotherapieUniversitätsklinikum FreiburgFreiburgDeutschland

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