Skip to main content

Advertisement

SpringerLink
Log in

Effects of fruiting body extracts of Lentinus edodes cultivated using corn cob on biological activities

  • Biotechnology
  • Published:
Korean Journal of Chemical Engineering Aims and scope Submit manuscript

Abstract

We investigated the antioxidant, nitrite scavenging, immune-enhancing and antimicrobial effects of the Lentinus edodes fruiting body extracts (LEFB extract) cultivated in the solid state using corn cob. The CAT, SOD and GSH-Px activities in the LEFB extract (400mg)-fed group were approximately 1.70, 1.64, and 2.2 times higher than those of the control group. The nitrite scavenging activity was highest (86.4%) when the LEFB extract concentration was 600 μg/mL. The immune-enhancing and antimicrobial effects of LEFB extract after an experimental Bordetella bronchiseptica infection were examined. White blood and neutrophil in the LEFB extract (400 mg)-fed group were approximately 2.1 and 2.2 times higher, respectively, than those of the control group. The total leukocyte was 30% higher than that of the control group. The CD4: CD8 ratio in the LEFB extract (200 mg)-fed group was increased approximately 54.3% compared to that of the control group. The levels of TNF-α and IFN-γ mRNA expression in the LEFB extract (400 mg)-fed group were approximately 49 and 50% lower than those of the control group. The bacteria and inflammatory cell in the LEFB extract (400 mg)-fed group were approximately 48.7 and 29% lower, respectively, than that of the control group. These results suggest that the LEFB extract may be useful in immune function improvement.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. S. T. Chang, Int. J. Med. Mushr., 1, 387 (1999).

    Article  Google Scholar 

  2. H. Lee, M. Song, Y. Yu and S. Hwang, Biochem. Eng. J., 15, 93 (2003).

    Article  CAS  Google Scholar 

  3. E. M. Park, S. J. Kim, E. J. Ye, M. J. Bae and K. C. Jo, J. Korean Soc. Food Sci. Nutr., 34, 323 (2005).

    Article  Google Scholar 

  4. S. J. Lee, S. M. Moon, T. Kim, J. Y. Kim, J. S. Seo, D. S. Kim, J. Kim, Y. J. Kim and Y. L. Park, Korean J. Microbiol. Biotechnol., 4, 362 (2003).

    Google Scholar 

  5. O. O. Kuforiji and I. O. Fasidi, Bioresour. Technol., 12, 4275 (2008).

    Article  Google Scholar 

  6. G. B. Bhak, M. K. Song, S. Y. Lee and S. H. Hwang, Biotechnol. Lett., 27, 1537 (2005).

    Article  CAS  Google Scholar 

  7. S. R. Cristina, G. R. Ana, P. Isabel, J. B. Gemma, R. M. Francisco and H. Wichers, Int. Biodeter. Biodegrad., 57, 37 (2006).

    Article  Google Scholar 

  8. K. H. Jang, K. O. Shin and S. D. Kim, Korean J. Food Preserv., 12, 379 (2005).

    Google Scholar 

  9. H. K. Zdena, E. Julia and E. Anna, Ind. Crops Products, 9, 101 (1999).

    Article  Google Scholar 

  10. B. Rivas, J. M. Dominguez, H. Dominguez and J. C. Parajo, Enzyme Technol., 31, 431 (2002).

    Article  CAS  Google Scholar 

  11. Q. Cao, K. C. Xie, W. R. Bao and S. G. Shen, Bioresour. Technol., 94, 83 (2004).

    Article  CAS  Google Scholar 

  12. N. I. Perotti and O. E. Molina, Biological Waste, 26, 125 (1988).

    Article  Google Scholar 

  13. W. T. Tsai, C. Y. Chang, S. Y. Wan, C. F. Chang, S. F. Chien and H. F. Sun, Bioresour. Technol., 78, 203 (2001).

    Article  CAS  Google Scholar 

  14. S. Ninawe and R. C. Kuhad, J. Appl. Microb., 99, 1141 (2005).

    Article  CAS  Google Scholar 

  15. K. Tota, J. I. Horicuchi, T. Kanno and M. Kobayashi, J. Biosci. Bioeng., 98, 228 (2004).

    Google Scholar 

  16. J. S. Ki, G. Y. Seo, I. S. Kang, B. K. Ahn and D. B. Choi, J. Adv. Eng. Technol., 3, 115 (2010).

    Google Scholar 

  17. W. S. Cha, S. S. Park, S. J. Kim and D. B. Choi, Bioresour. Technol., 101, 6475 (2010).

    Article  CAS  Google Scholar 

  18. B. H. Kim, D. B. Choi, Y. L. Piao, S. S. Park, M. K. Lee, W. S. Cha, Y. C. Chang and H. Cho, Korean J. Chem. Eng., 29(10), 1393 (2012).

    Article  CAS  Google Scholar 

  19. A. T. Yap and M. L. Ng, Inter. J. Med. Mush., 5, 339 (2003).

    Article  CAS  Google Scholar 

  20. H. J. Lee and Y. W. Seo, Biotechnol. Bioprocess Eng., 11, 13 (2006).

    Article  CAS  Google Scholar 

  21. D. B. Choi, H. G. Nam and W. S. Cha, Korean J. Chem. Eng., 23, 241 (2006).

    Article  CAS  Google Scholar 

  22. D. B. Choi, S. S. Park, J. L. Ding and W. S. Cha, Biotechnol. Bioprocess Eng., 12, 516 (2007).

    Article  CAS  Google Scholar 

  23. W. S. Cha, J. L. Ding and D. B. Choi, Biotechnol. Bioprocess Eng., 14, 232 (2009).

    Article  CAS  Google Scholar 

  24. D. B. Choi, Y. S. Kim, H. G. Nam, H. J. Shin, M. S. Na, O. Y. Choi, H. D. Lee and W. S. Cha, Korean J. Chem. Eng., 28(5), 1266 (2011).

    Article  CAS  Google Scholar 

  25. D. B. Choi, K. A. Cho, M. S. Na, H. S. Choi, Y. O. Kim, D. H. Lim, S. J. Cho and H. Cho, J. Ind. Eng. Chem., 14, 765 (2008).

    Article  CAS  Google Scholar 

  26. H. S. Choi, D. B. Choi, M. S. Na, K. A. Cho and M. Y. Lee, J. Ind. Eng. Chem., 15, 275 (2009).

    Article  CAS  Google Scholar 

  27. D. H. Lim, D. B. Choi, O. Y. Choi, K. A. Cho, R. Kim, H. S. Choi and H. Cho, J. Ind. Eng. Chem., 17, 510 (2011).

    Article  CAS  Google Scholar 

  28. F. Shahidi and P. K. J. Wanasundara, Crit. Rev. Food Sci. Nutr., 32, 67 (1992).

    Article  CAS  Google Scholar 

  29. J. S. Beckman and W. H. Koppenol, Am. J. Phys., 217, 1421 (1996).

    Google Scholar 

  30. B. G. Jung, J. H. Ko, S. J. Choi, H. B. Koh, S. H. Yoon, D. U. Han and B. J. Lee, J. Vet. Med. Sci., 72, 1195 (2010).

    Article  CAS  Google Scholar 

  31. J. MacMicking, Q. W. Xie and C. Nathan, Annu. Rev. Immunol., 15, 323 (1997).

    Article  CAS  Google Scholar 

  32. S. Moncada, R. M. J. Palmer and E. A. Higgs, Pharmacol. Rev., 43, 109 (1991).

    CAS  Google Scholar 

  33. P. Ghezzi and A. Cerami, Mol. Biotechnol., 31, 239 (2005).

    Article  CAS  Google Scholar 

  34. D. Branellec and S. Chouaib, Pathol. Biol., 39, 230 (1991).

    CAS  Google Scholar 

  35. D. B. Choi, J. H. Lee, Y. S. Kim, M. S. Na, O. Y. Choi, H. D. Lee, M. K. Lee and W. S. Cha, Korean J. Chem. Eng., 28(6), 1427 (2011).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. School of Chemical Engineering, Chonbuk National University, Jeonju, 561-756, Korea

    Jong-Soo Kim

  2. Department of Pharmacy, College of Pharmacy, Chungbuk National University, Cheongju, 361-763, Korea

    Dubok Choi & Myung Koo Lee

  3. College of Veterinary Medicine, Chonnam National University, Gwangju, 500-757, Korea

    Bock-Gie Jung & Bong-Joo Lee

  4. Interdisciplinary Program of Perfume and Cosmetics, Chonnam National University Graduate School, Gwangju, 500-757, Korea

    Geum-Sook Lim

  5. Department of Polymer Science & Engineering, Chosun University, Gwangju, 501-759, Korea

    Wol-Suk Cha & Hoon Cho

Authors
  1. Jong-Soo Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Dubok Choi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Bock-Gie Jung
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Bong-Joo Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Geum-Sook Lim
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Myung Koo Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Wol-Suk Cha
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Hoon Cho
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hoon Cho.

Additional information

These authors contributed equally to this work.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kim, JS., Choi, D., Jung, BG. et al. Effects of fruiting body extracts of Lentinus edodes cultivated using corn cob on biological activities. Korean J. Chem. Eng. 30, 906–912 (2013). https://doi.org/10.1007/s11814-012-0209-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11814-012-0209-7

Key words

Search

Navigation