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Characterization of PVA/glycerin hydrogels made by γ-irradiation for advanced wound dressings

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Abstract

The aim of this study was to investigate the enhanced absorption property of PVA/Glycerin (PVA/Gly) hydrogel for advanced wound dressing. A simple crosslinking method was introduced to prepare the PVA/Gly hydrogels with the use of γ-irradiation. An absorption ratio and thermal properties of the PVA/Gly hydrogels can be controlled by varying the irradiation dose and weight ratio of the PVA/Gly. When the PVA/Gly content was 20/5 wt% and the irradiation dose at 25 kGy, the PVA/Gly hydrogels showed excellent absorption properties (>350%). These results imply that the PVA/Gly hydrogel is highly absorbent and converts wound exudates to the hydrogel matrices that create a moist and clean environment in the wound healing process. Therefore, the PVA/Gly hydrogel prepared by this method can be used as an advanced wound dressing.

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Authors and Affiliations

  1. Radiation Research Center for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, 1266 Sinjeong-dong, Jeongeup-si, Jeonbuk, 580-185, Korea

    Hui-Jeong Gwon, Youn-Mook Lim, Sung-Jun An, Min-Ho Youn, Seol-Hee Han & Young-Chang Nho

  2. Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science Technology, Daejeon, 305-701, Korea

    Hui-Jeong Gwon & Ho-Nam Chang

Authors
  1. Hui-Jeong Gwon
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  2. Youn-Mook Lim
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  3. Sung-Jun An
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  4. Min-Ho Youn
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  5. Seol-Hee Han
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  6. Ho-Nam Chang
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  7. Young-Chang Nho
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Correspondence to Young-Chang Nho.

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Gwon, HJ., Lim, YM., An, SJ. et al. Characterization of PVA/glycerin hydrogels made by γ-irradiation for advanced wound dressings. Korean J. Chem. Eng. 26, 1686–1688 (2009). https://doi.org/10.1007/s11814-009-0246-z

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  • DOI: https://doi.org/10.1007/s11814-009-0246-z

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