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Computer aided modeling and pore distribution of bionic porous bone structure

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Abstract

Artificial bone with porous structure is crucial for tissue scaffold and clinic implants. Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure. A computational aided process of porous bone modeling was developed which described the design and fabrication of tissue scaffolds by considering intricate architecture, porosity and pore size. To simulate intricate bone structure, different constructive units were presented. In modeling process, bone contour was gotten from computed tomography (CT) images and was divided into two levels. Each level was represented by relatively reconstructive process. Pore size distribution was controlled by using mesh generation. The whole hexahedral mesh was reduced by unit structure, when a 3D mesh with various hexahedral elements was provided. The simulation results show that constructive structure of porous scaffold can meet the needs of clinic implants in accurate and controlled way

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Authors and Affiliations

  1. School of Mechanical Engineering and Automation, Northeastern University, Shenyang, 110819, China

    Hu Li  (李虎), Jian-yu Yang  (杨建宇) & Wan-shan Wang  (王宛山)

  2. State Key Laboratory of Tunnel Boring Machine (Northern Heavy Industries Group), Shenyang, 110141, China

    Peng-cheng Su  (苏鹏程)

Authors
  1. Hu Li  (李虎)
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  2. Jian-yu Yang  (杨建宇)
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  3. Peng-cheng Su  (苏鹏程)
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  4. Wan-shan Wang  (王宛山)
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Corresponding author

Correspondence to Hu Li  (李虎).

Additional information

Foundation item: Project(2011DFB70230)supported by State International Cooperation Program of China; Project(N110403003) supported by Basic Research Foundation of Education Ministry of China

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Li, H., Yang, Jy., Su, Pc. et al. Computer aided modeling and pore distribution of bionic porous bone structure. J. Cent. South Univ. 19, 3492–3499 (2012). https://doi.org/10.1007/s11771-012-1434-2

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  • DOI: https://doi.org/10.1007/s11771-012-1434-2

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