Abstract
A 3D temperature field distribution of biological tissue for superficial hyperthermia using a pulse modulated microwave (PMMW) was presented. A 3D sliced homogeneous phantom was radiated by the PMMW and an infrared thermal imager was applied to image temperature distribution throughout the phantom. The period of the PMMW is 3 s and the output power is 35 W. The temperature rises by at least 3 °C in the phantom when the duty cycle varies from 1/3, 1/2, 2/3 to 1 (denoted by scenarios 1–4). Both the accumulative temperature-volume histogram and the relative depth-area ratio histogram show that the maximum temperature rise (MTR) is 6.6 and 8 °C in scenarios 2 and 3, and they are superior to scenarios 1 and 4. Furthermore, the PMMW can control temperature field distribution of biological tissue. It provides both preliminary basis for thermal volume control and new technology for temperature control and monitor in superficial hyperthermia.
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References
BANSAL R. Battling cancer: The latest on microwave hyperthermia [J]. IEEE Microwave Magazine, 2005, 6(3): 32–34.
ZASTROW E, HAGNESS S C, van VEEN B D. 3D computational study of non-invasive patient-specific microwave hyperthermia treatment of breast cancer [J]. Physics in Medicine and Biology, 2010, 55(13): 3611–3629.
ZAGAR T M, OLESON J R, VUJASKOVIC Z, DEWHIRST M W, CRACIUNESCU O I, BLACKWELL K L, PROSNITZ L R, JONES E L. Hyperthermia combined with radiation therapy for superficial breast cancer and chest wall recurrence: A review of the randomised data [J]. International Journal of Hyperthermia, 2010, 26(7): 612–617.
FEYERABEND T, WIEDEMANN G J, JAGER B, VESELY H, MAHLMANN B, RICHTER E. Local hyperthermia, radiation, and chemotherapy in recurrent breast cancer is feasible and effective except for inflammatory disease [J]. International Journal of Radiation Oncology Biology Physics, 2001, 49(5): 1317–1325.
HAND J W. The current status of microwave induced hyperthermia and radiotherapy for the treatment of recurrent breast cancer [C]// IEE Electronics Division Colloquium on the Application of Microwaves in Medicine. London, IEE Press, 1995: 1–6.
ZASTROW E, DAVIS S K, LAZEBNIK M, KELCZ F, VAN VEEN B D, HAGNESS S C. Development of anatomically realistic numerical breast phantoms with accurate dielectric properties for modeling microwave interactions with the human breast [J]. IEEE Transactions on Biomedical Engineering, 2008, 55(12): 2792–2800.
SAITO K, YOSHIMURA H, ITO K, AOYAGI Y, HORITA H. Clinical trials of interstitial microwave hyperthermia by use of coaxial-slot antenna with two slots [J]. IEEE Transactions on Microwave Theory and Techniques, 2004, 52(8II): 1987–1991.
DE BRUIJNE M, WIELHEESEN D H, van der ZEE J, CHAVANNES N, van RHOON G C. Benefits of superficial hyperthermia treatment planning: Five case studies [J]. International Journal of Hyperthermia, 2007, 23(5): 417–429.
MACCARINI P, ROLFSNES H O, NEUMANN D, JOHNSON J, JUANG T, STAUFFER P. Advances in microwave hyperthermia of large superficial tumors [C]// IEEE MTT-S International Microwave Symposium Digest. Long Beach, USA. IEEE Press, 2005: 1796–1800.
PLANCOT M. A new method for thermal dosimetry in microwave hyperthermia using microwave radiometry for temperature control [J]. International Journal of Hyperthermia, 1987, 3(1): 9–19.
CRESSON P Y, DUBOIS L, PRIBETICH J. Determination of the optimal heating pattern obtained with external planar applicators used for 915 MHz microwave hyperthermia [C]// Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Lyon, France: IEEE Press, 2007: 1160–1163.
ARORA D, SKLIAR M, ROEMER R B. Minimum-time thermal dose control of thermal therapies [J]. IEEE Transactions on Biomedical Engineering, 2005, 52(2): 191–200.
GAMAGAMI P, SILVERSTEIN M J, WAISMAN J R. Infra-red imaging in breast cancer [C]// Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Chicago, USA. IEEE Press, 1997: 677–680.
PENNES H H. Analysis of tissue and arterial blood temperatures in the resting human forearm [J]. Journal of Applied Physiology, 1998, 85(1): 5–34.
NEUMAN D G, STAUFFER P R, JACOBSEN S, ROSSETTO F. SAR pattern perturbations from resonance effects in water bolus layers used with superficial microwave hyperthermia applicators [J]. International Journal of Hyperthermia, 2002, 18(3): 180–193.
SIAUVE N, NICOLAS L, VOLLAIRE C, MARCHAL C. 3D modelling of electromagnetic fields in local hyperthermia [J]. EPJ Applied Physics, 2003, 21(3): 243–250.
CORREIA D, KOK H P, DE GREEF M, BEL A, VAN WIERINGEN N, CREZEE J. Body conformal antennas for superficial hyperthermia: The impact of bending contact flexible microstrip applicators on their electromagnetic behavior [J]. IEEE Transactions on Biomedical Engineering, 2009, 56(12): 2917–2926.
JOHNSON J E, MACCARINI P F, NEUMAN D, STAUFFER P R. Automatic temperature controller for multielement array hyperthermia systems [J]. IEEE Transactions on Biomedical Engineering, 2006, 53(6): 1006–1015.
HE X, MCGEE S, COAD J E, SCHMIDLIN F, IAIZZO P A, SWANLUND D J, KLUGE S, RUDIE E, BISCHOF J C. Investigation of the thermal and tissue injury behaviour in microwave thermal therapy using a porcine kidney model [J]. International Journal of Hyperthermia, 2004, 20(6): 567–593.
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Foundation item: Project(50977064) supported by the National Natural Science Foundation of China
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Ma, Gj., Jiang, Gt. & Chen, Zh. Pulse modulated microwave and infrared thermography for superficial hyperthermia. J. Cent. South Univ. 19, 1927–1931 (2012). https://doi.org/10.1007/s11771-012-1227-7
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DOI: https://doi.org/10.1007/s11771-012-1227-7