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15-year outcomes of the JOCRI study (JOCRIED study): a randomised comparison of off-pump and on-pump multiple arterial coronary revascularisation

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Abstract

Objective

The Japanese Off-Pump Coronary Revascularization Investigation (JOCRI) study reported a non-significant difference in early outcomes and graft patency between off-pump coronary artery bypass grafting and on-pump coronary artery bypass grafting in 2005. The JOCRIED study aimed to review the long-term outcomes of the JOCRI study participants.

Method and results

The JOCRIED study enrolled 123 of the JOCRI study participants completing the clinical follow-up between August 2018 and August 2020; 61 patients in the off-pump group and 62 patients in the on-pump group. The follow-up period was 13.8 ± 2.8 years. The groups were compared regarding mortality, the incidence of major adverse cardiac and cerebrovascular events and repeat revascularisation. The 15-year cumulative survival rate (off-pump vs on-pump, respectively; 77.7% vs 75.3%; p = 0.85), major adverse events-free survival rate (62.5% vs 55.6%; p = 0.27) and repeat revascularisation-free rate (84.8% vs 78.0%; p = 0.16) were not significantly different between the two groups. Revascularisation was the most common major adverse events in the JOCRIED participants. Although percutaneous coronary intervention was performed in 8 patients (13%) in the off-pump group and in 14 patients (23%) in the on-pump group (p = 0.23), no patients underwent redo coronary artery bypass grafting.

Conclusions

Off-pump coronary artery bypass grafting provides comparable 15-year outcomes to on-pump coronary artery bypass grafting.

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Acknowledgements

We thank Jane Charbonneau, DVM, from Edanz (https://jp.edanz.com/ac) for editing a draft of this manuscript.

Disclosures

This work was not supported by a specific grant from any funding agency in the public, commercial or not-for-profit sectors.

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Authors and Affiliations

  1. Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, 6-1 Kishibeshimmachi, Suita, Osaka, Japan

    Naoki Tadokoro, Satsuki Fukushima, Yusuke Shimahara, Naonori Kawamoto, Takashi Kakuta, Junjiro Kobayashi & Tomoyuki Fujita

  2. Department of Cardiovascular Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

    Naoki Tadokoro & Hideyuki Shimizu

  3. Department of Surgical Intensive Care, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

    Kimito Minami

  4. Division of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, Japan

    Satoshi Numata & Hitoshi Yaku

  5. Department of Thoracic, Cardiovascular and General Surgery, Kanazawa University, Takara-machi, Kanazawa, Japan

    Hirofumi Takemura & Kenji Iino

  6. Department of Cardiovascular Surgery, Nippon Medical School, Bunkyo-Ku, Tokyo, Japan

    Masami Ochi & Yosuke Ishii

  7. Department of Cardiovascular Surgery, Fukuoka University, Fukuoka, Japan

    Hideichi Wada & Noritoshi Minematsu

Authors
  1. Naoki Tadokoro
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Contributions

All authors contributed to the content of the article by designing this work; participating in data collection, analysis and interpretation; drafting and revising the manuscript and approving the final version of the manuscript. All authors agree to submission of the final version of the manuscript.

Corresponding author

Correspondence to Satsuki Fukushima.

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None declared.

IRB information

This study was approved by the National Cerebral and Cardiovascular Center review board (Approval Number: M30-024).

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Tadokoro, N., Fukushima, S., Minami, K. et al. 15-year outcomes of the JOCRI study (JOCRIED study): a randomised comparison of off-pump and on-pump multiple arterial coronary revascularisation. Gen Thorac Cardiovasc Surg 71, 151–157 (2023). https://doi.org/10.1007/s11748-022-01854-y

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  • DOI: https://doi.org/10.1007/s11748-022-01854-y

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