Abstract
Autosomal dominant polycystic kidney disease is a systemic disorder associated with cardiovascular complications. However, there are few reports on autosomal dominant polycystic kidney disease-associated aortic dissection. Herein, we present a rare case of a 46-year-old man with autosomal dominant polycystic kidney disease who underwent endovascular repair for acute type B aortic dissection three years after his initial open surgery for acute type A aortic dissection. The postoperative course was uneventful, and he is doing well two years after the endovascular repair. Clinicians should be aware of the potential for occurrence of aortic dissection in patients with autosomal dominant polycystic kidney disease, including the possibility of recurrence.
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References
Ecder T. Cardiovascular complications in autosomal dominant polycystic kidney disease. Curr Hypertens Rev. 2013;9:2–11.
Silverio A, Prota C, Di Maio M, Polito MV, Cogliani FM, Citro R, et al. Aortic dissection in patients with autosomal dominant polycystic kidney disease: a series of two cases and a review of the literature. Nephrology (Carlton). 2015;20:229–35.
Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Eusanio MD, Sechtem U, et al. Insights from the International Registry of Acute Aortic Dissection: a 20-year experience of collaborative clinical research. Circulation. 2018;137:1846–60.
Torres VE. Systemic manifestations of renal cystic disease. In: Gardner KD, Berstein J, editors. The cystic kidney. Dordrecht: Kluwer; 1990. p. 295–326.
Sung PH, Yang YH, Chiang HJ, Chiang JY, Chen CJ, Liu CT, et al. Risk of aortic aneurysm and dissection in patients with autosomal-dominant polycystic kidney disease: a nationwide population-based cohort study. Oncotarget. 2017;8:57594–604.
Keuleers S, Verbeken E, Sinnaeve P. Aortic dissection associated with segmental arterial mediolysis in polycystic kidney disease. Eur J Intern Med. 2009;20:e9-11.
Kim K, Drummond I, Ibraghimov-Beskrovnaya O, Klinger K, Arnaout MA. Polycystin 1 is required for the structural integrity of blood vessels. Proc Natl Acad Sci USA. 2000;97:1731–6.
Griffin MD, Torres VE, Grande JP, Kumar R. Vascular expression of polycystin. J Am Soc Nephrol. 1997;8:616–26.
Isselbacher EM, Bonaca MP, Di Eusanio M, Froehlich J, Bassone E, Sechtem U, et al. Recurrent aortic dissection: observations from the International Registry of Aortic Dissection. Circulation. 2016;134:1013–24.
Ramineni R, Daniel GK. Use of endovascular stent-graft repair for type B aortic dissection in polycystic kidney disease. J Invasive Cardiol. 2010;22:E171–4.
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We thank Editage (http://www.editage.jp) for English language editing. We also thank Dr. Takumi Kitaoka for the histopathological consultation.
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Kobayashi, K., Kuroda, Y., Nakai, S. et al. Repeated aortic dissection in a patient with autosomal dominant polycystic kidney disease. Gen Thorac Cardiovasc Surg 70, 390–393 (2022). https://doi.org/10.1007/s11748-021-01756-5
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DOI: https://doi.org/10.1007/s11748-021-01756-5