Abstract
Left‐unilateral single‐lobe lung transplantation from a living donor was performed in a 4-year-old boy who suffered from severe respiratory failure caused by bronchiolitis obliterans (BO) as a result of graft versus host disease (GVHD) after peripheral blood stem cell transplantation (PBSCT). The patient grew well during his early childhood years, with an excellent lung allograft function. However, severe thoracic scoliosis occurred 7 years after lung transplantation, which ultimately resulted in compression of the lung allograft followed by severe respiratory dysfunction, and the patient became dependent on mechanical ventilation support. Posterior spinal fusion of Th2‐L3 with instrumentation and bone grafting was performed to correct scoliosis in the hope of recovering his thoracic capacity. The left thoracic volume was dramatically improved immediately after spinal fusion surgery, and the patient was ultimately weaned off of mechanical ventilation after a year of pulmonary rehabilitation.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Date H, Shiraishi T, Sugimoto S, Shoji T, Chen F, Hiratsuka M, Aoyama A, Sato M, Yamane M, Iwasaki A, Miyoshi S, Bando T, Oto T. Outcome of living-donor lobar lung transplantation using a single donor. J Thorac Cardiovasc Surg. 2012;144(3):710–5.
Shiraishi T, Hiratsuka M, Munakata M, Higuchi T, Makihata S, Yoshinaga Y, Yamamoto S, Iwasaki A, Yasumoto M, Hamada T, Higa K, Kuraki T, Watanabe K, Morishige N, Tashiro T, Nabeshima K, Kawahara K, Okabayashi K, Yasunaga H, Shirakusa T. Living-donor single-lobe lung transplantation for bronchiolitis obliterans in a 4-year-old child. J Thorac Cardiovasc Surg. 2007;134(4):1092–3.
Gollogly S, Smith JT, White SK, Firth S, White K. The volume of lung parenchyma as a function of age: a review of 1050 normal CT-scans of the chest with three-dimensional volumetric reconstruction of the pulmonary system. Spine. 2004;29:2061–6.
Hiratsuka M, Shiraishi T, Takao H, Akinori I. Long-term follow-up of living-donor single-lobe lung transplantation for bronchiolitis obliterans in a four-year-old male: improvement of over-sized lung allograft. Interac Cardiovasc Thorac Surgery. 2011;13(1):114–6.
Horne JP, Flannery R, Usman S. Adolescent Idiopathic Scoliosis: Diagnosis and Management. Am Fam Physician. 2014;89(3):193–8.
Eren S, Nesimi EM, Balci AE. Pneumonectomy in children for destroyed lung and the long-term consequences. J Thorac Cardiovasc Surg. 2003;126:574–81.
Lezama-del VP, Blakely ML, Lobe TE. Long-term consequences of pneumonectomy done in children. In: Deslauries J, Faber LP, editors. Chest surgery clinics of North America. Philadelphia: Saunders; 1999. p. 485–495.
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Shiraishi, T., Yanagida, H., Koga, Y. et al. Severe scoliosis with an impaired pulmonary allograft function after pediatric unilateral lung transplantation. Gen Thorac Cardiovasc Surg 69, 375–378 (2021). https://doi.org/10.1007/s11748-020-01447-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11748-020-01447-7