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Quality assessment using EQ-5D-5L after lung surgery for non-small cell lung cancer (NSCLC) patients

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Abstract

Objectives

Aim of this study was to elucidate an alteration of quality of life (QOL) score before and after video-assisted thoracoscopic surgery (VATS) for non-small cell lung cancer (NSCLC) patients using the 5-level EuroQol-5D questionnaire (EQ-5D-5L). We also investigated how the preoperative QOL scores affected the postoperative clinical outcome prospectively.

Methods

Between July 2018 and December 2018, 24 consecutive NSCLC patients who underwent VATS were recruited. The EQ-5D-5L for Japanese was used with face-to-face interviews to estimate the utility values of QOL.

Results

QOL scores were significantly declined after surgery (0.81 ± 0.19 vs. 0.74 ± 0.11: P = 0.049). The levels of EQ-5D-5L questionnaire were not significantly different before and after surgery except Q4 (pain control). The levels of Q4 were significantly worsened after surgery (1.33 ± 0.56 vs. 1.88 ± 0.61, P < 0.001). Operation time and bleeding in the preoperative low-QOL score group (N = 13) was longer (215.4 ± 52.3 min. vs. 173.5 ± 42.3 min., respectively: P = 0.045) and more (116.2 ± 152.7 ml vs. 22.7 ± 20.1 ml, respectively: P = 0.049) than those in the high-QOL score group (N = 11).

Conclusions

QOL survey for lung cancer patients using EQ-5D-5L is simple and useful to identify the issue facing at the medical team. Preoperative low QOL score could be a predicting factor for the longer operation time and more bleeding.

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Acknowledgements

Supported by Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan, no. 17K10672 to T. Mizuguchi. Part of the study was also supported by Astellas Pharma Inc. (Tokyo, Japan), Daiichi Sankyo Company (Tokyo, Japan), Shionogi & Co. (Osaka, Japan), Sapporo Doto Hospital (Sapporo, Japan), Noguchi Hospital (Otaru, Japan), Doki-kai Tomakomai Hospital (Tomakomai, Japan), Tsuchida Hospital (Sapporo, Japan) and Ikuta Hospital (Shiraoi, Japan).

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Authors and Affiliations

  1. Department of Nursing I, Sapporo Medical University Postgraduate School of Health Science, S-1, W-17, Chuo-Ku, Sapporo, Hokkaido, 060-8556, Japan

    Ryo Koide, Ami Kikuchi, Izumi Sawada & Toru Mizuguchi

  2. Department of Nursing, Division of Surgical Science, Sapporo Medical University Postgraduate School of Health Science, S-1, W-17, Chuo-Ku, Sapporo, Hokkaido, 060-8556, Japan

    Ryo Koide, Ami Kikuchi & Toru Mizuguchi

  3. Department of Thoracic Surgery, Sapporo Medical University Postgraduate School of Medicine, S-1, W-16, Chuo-Ku, Sapporo, Hokkaido, 060-8543, Japan

    Masahiro Miyajima, Taijiro Mishina, Yuki Takahashi, Miho Okawa, Junko Nakajima & Atsushi Watanabe

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  1. Ryo Koide
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  2. Ami Kikuchi
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  3. Masahiro Miyajima
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Correspondence to Toru Mizuguchi.

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Ryo Koide and other co-authors have no conflict of interest.

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Koide, R., Kikuchi, A., Miyajima, M. et al. Quality assessment using EQ-5D-5L after lung surgery for non-small cell lung cancer (NSCLC) patients. Gen Thorac Cardiovasc Surg 67, 1056–1061 (2019). https://doi.org/10.1007/s11748-019-01136-0

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  • DOI: https://doi.org/10.1007/s11748-019-01136-0

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